At the American Society for Clinical Oncology (ASCO) Annual Meeting 2016, researchers present results of three clinical trials using new targeted therapies against triple negative breast cancer (TNBC). Each therapy uses a ...
Jun 3, 2016
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Anti-cancer effect of tumor infiltrating CD8+T lymphocyte (CD8TIL) is suppressed by interaction between immune-checkpoint molecules such as PD-1 and CTLA-4 expressed on CD8TIL and their ligands expressed on cancer cells, ...
Feb 24, 2016
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Noninvasive sound technology developed at the University of Michigan breaks down liver tumors in rats, kills cancer cells and spurs the immune system to prevent further spread—an advance that could lead to improved cancer ...
Apr 18, 2022
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(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, undifferentiated ...
Pancreatic cancer is regarded as the cancer type with the lowest survival rates. Fewer than seven in 100 patients survive the first five years after diagnosis. Clinicians attribute this devastating prognosis to two circumstances: ...
Jun 1, 2016
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One of the reasons cancer cells are so robust against the body's natural defenses is that they are in fact human cells, and as such they have the innate machinery not only to trick the body's defense and maintenance systems, ...
Jul 24, 2019
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An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...
Dec 9, 2022
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Silibinin has an outstanding safety profile in humans and is currently used for the treatment of liver disease and poisoning. Scientists at the Max Planck Institute of Psychiatry in Munich discovered in collaboration with ...
Feb 10, 2015
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Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative ...
Mar 28, 2023
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When active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity are not available.
Sep 14, 2014
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