Medical research

Using nanocapsules to deliver vaccines to lungs

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish ...

Medications

Study identifies increase in antibiotic-resistant typhoid

A study in Malawi has shown that shortly after an increase in antimicrobial use—specifically the antibiotic ciprofloxacin—rates of antimicrobial-resistant Salmonella typhi increased.

Immunology

Resident T-cells key to Salmonella immunity, shows study

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease. New work from researchers at the UC Davis School ...

Diseases, Conditions, Syndromes

Rapid test delineates diseases with similar symptoms

Malaria and typhoid fever are major health problems in tropical regions, but accurate diagnosis is often hampered by overlapping or nonspecific symptoms and limited access to diagnostics. Now, NIBIB-funded scientists have ...

Medical research

Study finds key mechanism for how typhoid bacteria infects

A new study has uncovered key details for how the Salmonella bacteria that causes typhoid fever identifies a host's immune cells and delivers toxins that disrupt the immune system and allow the pathogen to spread.

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