Oncology & Cancer
Breakthrough drug on fast-track to help leukemia patients
Three very different people gathered recently at University of Colorado Hospital. They were linked by leukemia.
Feb 28, 2014
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Page 6 - News tagged with tyrosine kinase
Oncology & Cancer
Blueprint for next generation of chronic myeloid leukemia treatment
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have identified and characterized mutated forms of the gene that encodes BCR-ABL, the unregulated enzyme driving the blood cancer chronic myeloid leukemia ...
Aug 20, 2014
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Medical research
New model for predicting neuroblastoma outcomes incorporates early developmental signals
Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops ...
Jul 6, 2018
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Oncology & Cancer
Study suggests drug intervention may prevent doxorubicin-induced cardiac injury
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.
Jan 25, 2021
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Oncology & Cancer
New drug shows potential for treatment-resistant leukemia
A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment.
Apr 11, 2011
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Medical research
Obese inducing brain mechanism
Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...
Sep 15, 2017
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Oncology & Cancer
Sorafenib effective in patients with non-small cell lung cancer, but low survival rates reported
Sorafenib was effective in patients with non-small cell lung cancer and a KRAS mutation, but survival rates were reportedly "unsatisfactory," according to data presented at the AACR-IASLC Joint Conference on Molecular Origins ...
Jan 10, 2012
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Oncology & Cancer
Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Jan 30, 2012
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Oncology & Cancer
Novel experimental agent is highly active in CLL patients, interim study shows
An interim analysis of a phase II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated both in patients who are undergoing treatment for the first ...
Jun 6, 2011
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Oncology & Cancer
Combination therapy shows promise for chronic myeloid leukemia
A study in mice combining two inhibitor drugs for treatment of chronic myeloid leukemia (CML) has revealed potential for not only stopping the disease completely, but also significantly lowering the cost for treatment. CML ...
Sep 7, 2016
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