Inflammatory disorders

Cancer drug helps combat asthma in mice

In a mouse model of allergic asthma, dasatinib—an enzyme inhibitor approved for the treatment of chronic myelogenous leukemia—reduced inflammation, enhanced airway repair, and improved lung mechanics.

Oncology & Cancer

Researchers study use of dasatinib for patients with high-risk MDS

Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, ...

Oncology & Cancer

Researchers identify drivers of sarcoma growth and survival

To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...

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