Oncology & Cancer
The uncharted role of HER2 mutant alleles in breast cancer
A new editorial paper titled "The uncharted role of HER2 mutant alleles in breast cancer has been published in Oncotarget.
Nov 6, 2023
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Page 25 - News tagged with tyrosine
Oncology & Cancer
Tumor suppressor protein targets liver cancer
Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth ...
Mar 29, 2018
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Diabetes
An experiment in mice palliates kidney disease caused by diabetes
Diabetes has become a major health problem worldwide; some estimates suggest that in 20 years, there will be around 600 million diabetics. The disease is caused by impaired insulin secretion, which in turn hinders cell glucose ...
Feb 8, 2018
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Medical research
Team reveals molecular pathway of weight-controlling hormone
Scientists at NGM Bio have revealed deep insights into the role that a little-understood human hormone plays in regulating body weight. Named Growth and Differentiation Factor 15 (GDF15), this hormone is typically active ...
Oct 2, 2017
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Oncology & Cancer
Updates: MET targeted therapy for EXON 14 mutations in lung cancer
A new editorial paper titled "Latest updates on MET targeted therapy for EXON 14 mutations in lung cancer" has been published in Oncotarget.
Sep 11, 2023
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Oncology & Cancer
Targeted oral therapy combo safe, effective for chronic lymphocytic leukemia
Acalabrutinib is a second-generation Bruton's tyrosine kinase (BTK) inhibitor, a newer class of drugs shown to improve the survival of patients with chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). Researchers ...
Dec 13, 2017
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Oncology & Cancer
A novel mechanism of crizotinib resistance in a ROS1+ NSCLC patient
Molecular analysis of a tumor biopsy from a proto-oncogene 1 receptor tyrosine kinase positive (ROS1+) patient with acquired crizotinib resistance revealed a novel mutation in the v-kit Hardy Zuckerman 4 feline sarcoma viral ...
Apr 11, 2016
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Oncology & Cancer
Molecular imaging signals new treatment protocol for kidney cancer
Research revealed at the Society of Nuclear Medicine's 2012 Annual Meeting explores treatment with a newly developed type of radioimmunotherapy used for treating a resistant form of kidney cancer. The agent is able to hone ...
Jun 11, 2012
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Oncology & Cancer
Anaplastic lymphoma kinase immunohistochemistry testing comparable to fluorescence in situ hybridization testing
Sixteen institutions across Europe collaborated together to show for the first time that a semi-quantitative anaplastic lymphoma kinase (ALK) protein expression test, immunohistochemistry (IHC), is reliable amongst several ...
Oct 23, 2014
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Oncology & Cancer
Sorafenib modestly increases progression-free survival
Sorafenib, a tyrosine kinase inhibitor (TKI) targeting the receptors for vascular endothelial growth factor, platelet derived growth factor, and mast/stem cell growth factor, modestly increases progression-free survival (PFS), ...
Nov 9, 2015
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