Diseases, Conditions, Syndromes

Exploring how poxviruses dismantle antiviral responses

Northwestern Medicine investigators led by Derek Walsh, Ph.D., professor of Microbiology-Immunology, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, ...

Diseases, Conditions, Syndromes

Investigating the smallpox blanket controversy

In Indian Country, it is an accepted fact that white settlers distributed items, such as blankets contaminated with smallpox and other infectious diseases, aiming to reduce the population of Native people resisting their ...


Monkeypox viruses remain sensitive to the available drugs

The mpox virus is closely related to the smallpox virus (variola virus), which caused large, deadly outbreaks before it was eradicated by vaccination at the end of the 1970s. While the smallpox virus led to very severe disease ...

Diseases, Conditions, Syndromes

Laboratory response network facilitates rapid ID of monkeypox

The Laboratory Response Network (LRN) has facilitated rapid testing and detection of patients with monkeypox, according to research published in the July 8 early-release issue of the U.S. Centers for Disease Control and ...

Diseases, Conditions, Syndromes

Remembering humanity's triumph over a virus, 40 years on

As scientists scramble for a COVID-19 cure and vaccine, the world on Friday marked a pertinent anniversary: humanity's only true triumph over an infectious disease with its eradication of smallpox four decades ago.

Diseases, Conditions, Syndromes

New clues on the history of the smallpox vaccine virus

Smallpox - simply hearing the word evokes images of countless people suffering gruesome deaths throughout recorded history. Known scientifically as variola, the virus had 30 percent mortality rate and survivors were branded ...