A cellular protein that interacts with invading viruses appears to help enable the infection process of the Zika virus, according to an international team of researchers who suggest this protein could be a key target in developing ...
Jan 15, 2019
0
39
The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli (EHEC), according to a study published January 10 in the open-access ...
Jan 10, 2019
0
0
The RIG-I like receptors (RLRs) are intracellular enzyme sentries that detect viral infection and initiate a first line of antiviral defense. The cellular molecules that activate RLRs in vivo are not clear.
Dec 14, 2018
0
64
Not all chronic hepatitis B (HBV) patients require lifelong treatment; but the risks of blindly withdrawing treatment can be severe. However, there's little consensus on which patients can be safely discontinued from treatment, ...
Nov 30, 2018
0
9
According to the US Center for Disease Control, the number of worldwide cases of poliomyelitis has decreased from 350,000 in 1988 to 407 in 2013. While the decline has been steady, polio has still not been eradicated. To ...
Aug 3, 2018
0
4
Antiretroviral therapies have worked wonders suppressing HIV replication and its progression to AIDS, but their effectiveness is deteriorating due to the constant development of drug resistance in the virus. Now Yale researchers ...
Jul 26, 2018
0
0
High doses of favipiravir extended survival in non-human primates infected with Ebola virus, according to a new study published this week in PLOS Medicine by Jeremie Guedj of INSERM, France, and colleagues.
Mar 27, 2018
0
5
Once herpes simplex infects a person, the virus goes into hiding inside nerve cells, hibernating there for life, periodically waking up from its sleep to reignite infection, causing cold sores or genital lesions to recur.
Mar 15, 2018
0
81
New research reveals details of the mechanism by which the bacterium Wolbachia blocks viruses in mosquito cells, suggesting that it reduces viral replication inside cells and that rapid degradation of viral RNA is involved. ...
Mar 1, 2018
0
18
Scientists at the Morgridge Institute for Research have discovered a new Achilles heel in the replication process of positive-strand RNA viruses, a class responsible for health threats such as Zika, polio, chikungunya and ...
Jan 24, 2018
0
53
