Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring. Researchers at the University of Zurich have now developed an immunotherapy that specifically targets the cause—activated ...
Sep 15, 2022
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Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more ...
May 10, 2022
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Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens ...
Jun 28, 2021
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The parasite causing the most severe form of human malaria uses proteins to make red blood cells sticky, making it harder for the immune system to destroy it and leading to potentially fatal blood clots. New research at the ...
Apr 13, 2020
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Common wisdom maintains that, because of the myriad effects on the brain, how anesthetic drugs work at the molecular level is a mystery.
Sep 11, 2017
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During a stroke or organ transplant, patients can suffer an injury due to lack of blood supply to vital organs. The injury—known as ischemia reperfusion—can cause damage to tissues. But a new Yale-led study has identified ...
Jun 21, 2017
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Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step ...
Mar 5, 2013
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Research has shown that mutations in the psen1 gene are common in the familial forms of Alzheimer's disease, and the Presenilin-1 protein that the gene encodes is known to be involved in the cleavage of the amyloid precursor ...
Feb 5, 2013
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The 20 proteins in the Wnt family are some of the most important proteins in controlling how an organism develops and grows, but for 30 years scientists have not known what these vital proteins actually look like. The proteins ...
May 31, 2012
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Sickle cell anemia causes pain, fatigue and delayed growth, all because of a lack of enough healthy red blood cells. And yet genetic mutations that cause it - recessive genes for the oxygen-carrying hemoglobin protein - have ...
Nov 30, 2011
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