Scientists at Duke-NUS Medical School have uncovered why some pancreatic and colorectal cancers fail to respond to Wnt inhibitors, a promising new class of cancer drugs currently under development for these cancers. Their ...
Apr 11, 2024
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Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide, and only around 10% of patients survive for five years after being diagnosed.
Sep 11, 2023
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A team of Mass Eye and Ear Scientists led by Albert Edge, Ph.D., working with research fellow Yushi Hayashi, MD, Ph.D., has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease. The researchers ...
Oct 5, 2021
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Kidney development is a balancing act between the self-renewal of stem and progenitor cells to maintain and expand their numbers, and the differentiation of these cells into more specialized cell types. In a new study in ...
Apr 1, 2021
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Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular ...
Nov 20, 2020
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Deleting the TSC2 gene in specific lung cells of mice led to the activation of the mTORC1 signaling pathway and pulmonary disease characteristics consistent with human LAM disease, particularly in female breeder mice. These ...
Nov 9, 2020
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A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Sep 15, 2020
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Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.
Aug 28, 2020
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New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit ...
Feb 7, 2019
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Scientists at the Oklahoma Medical Research Foundation have broken new ground in understanding how the lymphatic system works, potentially opening the door for future therapies.
Oct 16, 2018
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