The human body maintains a healthy layer of skin thanks to a population of stem cells that reside in the epidermis. Previously, the signals responsible for regulating these so-called 'interfollicular epidermal stem cells' ...
Jul 16, 2014
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Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.
May 30, 2012
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Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance ...
Apr 11, 2016
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Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment ...
May 23, 2011
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(Medical Xpress)—A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process that is activated across a vast ...
Jul 12, 2013
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Scientists have created a highly specific and well-characterised chemical probe which can switch off two important proteins implicated in cancer—shedding new light on the role these proteins play in driving cancer cell ...
Oct 26, 2015
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The 20 proteins in the Wnt family are some of the most important proteins in controlling how an organism develops and grows, but for 30 years scientists have not known what these vital proteins actually look like. The proteins ...
May 31, 2012
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Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that ...
Jan 30, 2014
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The liver is known for its ability to regenerate. It can completely regrow itself even after two-thirds of its mass has been surgically removed. But damage from medications, alcohol abuse or obesity can eventually cause the ...
Oct 17, 2022
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Researchers from Duke-NUS Medical School, Erasmus University Medical Center, Yale-NUS College and Duke University have found a potential way to predict who will respond to cancer therapies that block Wnt production, such ...
Nov 9, 2020
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