Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
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Scientists have revealed details of the discovery of new inhibitors of the BCL6 protein, which is involved in driving several cancer types including the blood cancer B-cell lymphoma.
Feb 9, 2023
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There have been many research efforts describing the nature and progression of dog allergies, but there have been very few applied studies that use this information to try to cure people of dog allergies entirely by artificially ...
Dec 22, 2021
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A molecule known as anaplastic lymphoma kinase (ALK) is a driver of several cancers, including pediatric neuroblastoma, B-cell lymphomas, and myofibroblast tumors. But for years much about this molecule—its role in the ...
Nov 26, 2021
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UT Southwestern researchers report the first structural confirmation that endogenous—or self-made—molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4/MD-2 receptor complex. ...
Jul 22, 2021
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Scientists at The University of Manchester have developed a more efficient method to produce medicines that are in development for the treatment of COVID-19, cancer and other diseases that affect many of the world's population.
May 20, 2021
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American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design—blocking a molecular "scissor" that the virus uses for virus production and to disable ...
Oct 16, 2020
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A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff—a virulent health care-associated infection that causes severe ...
Jan 3, 2020
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Researchers at Cardiff University have used X-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection.
Feb 19, 2019
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UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of ...
Jan 3, 2017
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