Medical research

Complex cellular machine visualized to yield new insights in cancer

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein ...

Oncology & Cancer

Overstuffed cancer cells may have an Achilles' heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry ...

Medical research

A moderate dose of novel form of stress promotes longevity

A newly described form of stress called chromatin architectural defect, or chromatin stress, triggers in cells a response that leads to a longer life. Researchers at Baylor College of Medicine and the Houston Methodist Research ...

Genetics

Effects of genes often influenced by network

When many genes regulate a single trait, they commonly work together in large clusters or 'networks". Taking this into account allows better predictions of how an individual's genetic make-up affects the trait concerned. ...

Oncology & Cancer

Spotting DNA repair genes gone awry

Researchers led by Ludwig Cancer Research scientist Richard Kolodner have developed a new technique for sussing out the genes responsible for helping repair DNA damage that, if left unchecked, can lead to certain cancers.

Genetics

Yeast against the machine: Bakers' yeast could improve diagnosis

It's easier than ever to sequence our DNA, but doctors still can't exactly tell from our genomes which diseases might befall us. Professor Fritz Roth is setting out to change this by going to basics—to our billion-year-old ...

Genetics

Slowing the ageing process—it's in your genes

Imagine being able to take a drug that can reduce the rate at which you age. Research by Massey University senior lecturer in genetics Dr Austen Ganley is making this dream one step closer to reality.

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