The research groups of Jeroen Bakkers (Hubrecht Institute/UMC Utrecht) and Toon van Veen (UMC Utrecht) report the first patient-specific model for the heart disease arrhythmogenic cardiomyopathy (ACM). They were able to simulate ...
Dec 9, 2021
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German scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they ...
Dec 5, 2012
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Northwestern Medicine scientists have identified disease-causing DNA variants in two genes linked to neurodevelopmental deficits including microcephaly in children, according to findings published in Nature Communications.
Dec 15, 2022
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Mitochondria play an essential role in supplying the energy needed for correct cell function. Within mitochondria, energy production is generated by the respiratory chain, which is formed of five complexes called CI through ...
May 13, 2024
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Researchers in the United Kingdom and Denmark have studied the "see-through" larvae of zebrafish to reveal how wound healing leads to skin cancer. Live imaging shows neutrophils, the protective inflammatory cells of the body's ...
Jul 1, 2015
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Researchers led by the Francis Crick Institute have developed a zebrafish model of a human disease - Hirschsprung disease - that enables them to study the disease's causes and consequences in living animals and will help ...
Jan 12, 2017
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Research in zebrafish has helped identify the cause of an unknown genetic disorder affecting a boy and two of his uncles, scientists report in an article published October 14 in the journal Genetics.
Oct 14, 2014
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Recent evidence suggests that dopamine plays a crucial role in neural development. In a novel study, investigators demonstrated the link between disrupted developmental dopamine signaling and autism spectrum disorder (ASD).
May 15, 2024
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Scientists at the National Eye Institute (NEI) have developed a zebrafish model of NEDBEH—a rare genetic disorder that can cause coloboma, where parts of the eye are missing due to developmental defects. The model provides ...
Jan 12, 2023
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Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder ...
Sep 12, 2014
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