Neuroscience

Stem cell-gene therapy shows promise in ALS safety trial

Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially ...

Neuroscience

New technique helps uncover changes in ALS neurons

Northwestern Medicine scientists have discovered that some neurons affected by amyotrophic lateral sclerosis (ALS) display hypo-excitability, using a new method to measure electrical activity in cells, according to a study ...

Neuroscience

Scientists identify new drug target to treat ALS

Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...

Alzheimer's disease & dementia

How much does dementia risk increase after traumatic brain injury?

Having a moderate or severe traumatic brain injury (TBI) in middle-age is associated with an increased risk for future dementia, according to a retrospective of study of more than 40,000 TBI patients published in PLOS Medicine ...

Medications

FDA panel narrowly sides against experimental ALS drug

Federal health advisers on Wednesday narrowly ruled against an experimental drug for the debilitating illness known as Lou Gehrig's disease, a potential setback for patient groups who have lobbied for the medication's approval.

Medical research

Experimental treatment slows prion disease, extends life of mice

Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives, according to a new report ...

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