A new study by researchers at Sanford-Burnham Medical Research Institute reveals the process that leads to changes in the brains of individuals with Down syndrome—the same changes that cause dementia in Alzheimer's patients. ...
Oct 23, 2014
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(Medical Xpress) -- Children with Down syndrome who learned to ride a two-wheel bike were less sedentary overall and had less body fat one year after learning to ride compared to those who did not participate, a University ...
Oct 12, 2011
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In one of the first studies of its kind, UCLA researchers used a unique brain scan to assess the levels of amyloid plaques and neurofibrillary tangles -- the hallmarks of Alzheimer's disease -- in adults with Down syndrome.
Jun 13, 2011
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Around 80% of people with Down syndrome develop Alzheimer's disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer's disease ...
Aug 24, 2022
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A newly available DNA-based prenatal blood test that can identify a pregnancy with Down syndrome can also identify two additional chromosome abnormalities: trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). The ...
Feb 2, 2012
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Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.
Mar 13, 2020
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Professor Juan Lerma's group, from the UMH-CSIC Institute of Neurosciences, in Alicante (Spain), has identified the gene called GRIK1, fundamental in the balance between excitation and inhibition in the brain, as one of the ...
Nov 1, 2019
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(Medical Xpress) -- New technology and innovations in genetic sequencing are dramatically changing the field of prenatal diagnosis and testing. Peter Benn, professor and director of the Diagnostic Human Genetics Laboratories ...
Nov 8, 2011
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Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain.
Mar 24, 2013
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The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. ...
Nov 18, 2022
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