Medical research

Research toward healing the hearts of children with Duchenne

After a progressive weakening of the muscles takes away their motor skills, and then their abilities to stand and walk, most males with Duchenne muscular dystrophy die of heart and respiratory failure in their 20s.

Genetics

CRISPR enhances gene therapy to fight inherited diseases

Gene therapy has shown promise in treating inherited genetic diseases, but a major issue that has frustrated scientists remains: Replacing a "bad" gene with a healthy one often is a short-lived fix. Typically, the healthy ...

Medical research

Muscle regeneration compromises stability in muscular dystrophy

A new study finds that muscle fibers in Duchenne muscular dystrophy (DMD) split during regeneration to such an extreme that the muscle is weakened beyond repair. The article is published ahead of print in the American Journal ...

Medical research

Muscular dystrophy clue

Patients with Duchenne muscular dystrophy (DMD) have a genetic mutation that causes incurable muscle degeneration. Research has shown that the immune system plays a complex, double-sided role in muscular dystrophy—promoting ...

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