Professor Simona Stäger and her team at INRS have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help ...
Aug 1, 2018
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The nectar of common plants such as sunflower contain bioactive agents that can inhibit the growth of Leishmania and could be used to help fight the potentially fatal disease caused by the parasite, say researchers.
Jun 2, 2022
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Brazilian researchers believe they have identified in patients treated at the University Hospital (HU) in Aracaju, state of Sergipe, a new species of parasite that can cause a disease similar to visceral leishmaniasis but ...
Oct 1, 2019
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Scientists have new evidence that a tropical disease once seen almost exclusively in returning travelers is now being detected in the United States in people with no international travel history—and caused by a Leishmania ...
Oct 19, 2023
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The Phlebotomus papatasi sandfly is responsible for spreading Leishmania throughout the tropics and subtropics. How individuals in areas endemic for Leishmania infection react to sandfly saliva depends on their long-term ...
Oct 12, 2017
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In an article in the latest issue of PLOS Pathogens, INRS professor Simona Stäger and her team show how the parasite Leishmania donovani uses a physiological response to low oxygen levels (hypoxia) to establish a chronic ...
Oct 4, 2017
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For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...
Nov 20, 2019
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A new preclinical candidate drug with the potential to treat visceral leishmaniasis, one of the world's major neglected diseases, has been discovered through a close collaboration between the University of Dundee, GSK and ...
Jul 25, 2018
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The parasitic disease leishmaniasis is found primarily in Central and South America, the Mediterranean region, the Middle East, and Central Asia and is transmitted to humans by a sand fly. An estimated 1.5 million new cases ...
Oct 24, 2023
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Scientists at the University of York have discovered that parasites responsible for leishmaniasis - a globally occurring neglected tropical disease spread by sand flies - are mainly acquired from the skin rather than a person's ...
Jul 5, 2017
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