Motor Neurone Disease
Hormone signal drives motor neuron growth, fish study shows
A discovery made in fish could aid research into motor neuron disease.
Medical research
May 23, 2013 |
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Italy approves law on controversial stem cell therapy (Update)
Italian lawmakers on Wednesday gave their final approval to a law that allows limited use of a controversial type of stem cell therapy which has been condemned by many scientists but has given hope to families of terminally-ill ...
Medical research
May 22, 2013 |
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Brain diseases affecting more people and starting earlier than ever before
Professor Colin Pritchard's latest research published in Public Health journal has found that the sharp rise of dementia and other neurological deaths in people under 74 cannot be put down to the fact that we are living longer ...
Health
May 10, 2013 |
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Structure that edits messenger RNA transcripts defective in two different forms of motor neuron diseases
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a ...
Medical research
Apr 26, 2013 |
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Increased stability of a misfolded protein linked to age of onset of common form of motor neuron disease
Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic ...
Medical research
Apr 22, 2013 |
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Reinventing drug discovery: Promising drug target for ALS
Using a new stem-cell based drug screening technology with the potential to reinvent and greatly reduce the cost of the way new pharmaceuticals are developed, Harvard Stem Cell Institute (HSCI) researchers ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
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'Strikingly similar' brains of man and fly may aid mental health research
A new study by scientists at King's College London and the University of Arizona (UA) published in Science reveals the deep similarities in how the brain regulates behaviour in arthropods (such as flies ...
Neuroscience
Apr 11, 2013 |
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Study offers new approach for spinal muscular atrophy
Spinal muscular atrophy is a debilitating neuromuscular disease that in its most severe form is the leading genetic cause of infant death. By experimenting with an ALS drug in two very different animal models, researchers ...
Neuroscience
Apr 09, 2013 |
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A fly mutation suggests a new route for tackling ALS
A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered ...
Genetics
Apr 08, 2013 |
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Lithium shows no benefit to MND patients
(Medical Xpress)—Results from a clinical trial into amyotrophic lateral sclerosis (ALS), led by King's College London's Institute of Psychiatry show that lithium carbonate is ineffective at treating the ...
Neuroscience
Mar 19, 2013 |
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Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone a ...
Neuroscience
Mar 14, 2013 |
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Mutated gene causes nerve cell death
Researchers identify new mechanism in the onset of incurable nerve disease The British astrophysicist Stephen Hawking is likely to be the world's most famous person living with amyotrophic lateral sclerosis ...
Medical research
Mar 13, 2013 |
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Ability of brain to protect itself from damage revealed
The origin of an innate ability the brain has to protect itself from damage that occurs in stroke has been explained for the first time.
Medical research
Feb 24, 2013 |
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Stem cell discovery gives insight into motor neurone disease
A discovery using stem cells from a patient with motor neurone disease could help research into treatments for the condition. The study used a patient's skin cells to create motor neurons - nerve cells that control muscle ...
Diseases, Conditions, Syndromes
Feb 11, 2013 |
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Researchers identify new genetic mutation for ALS
Researchers at Western University in London, Canada, have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), opening the door to future targeted therapies. Dr. Michael Strong, a scientist ...
Genetics
Jan 15, 2013 |
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The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause progressive disability and death. The drug riluzole can slow progression slightly; apart from this the medical care is supportive. The condition was first described in full by the French neurologist Jean-Martin Charcot in 1869.
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