Ovarian Cancer

Tiny genetic variation can predict ovarian cancer outcome

Yale Cancer Center researchers have shown that a tiny genetic variation predicts chances of survival and response to treatment for patients with ovarian cancer.

Cancer created Dec 05, 2011 | popularity not rated yet | comments 0 | with audio podcast

Vaccine for metastatic breast, ovarian cancer shows promise

Treatment with a recombinant poxviral vaccine showed a positive response in both metastatic breast cancer and ovarian cancer, according to a trial published in Clinical Cancer Research, a journal of the American Association for Ca ...

Cancer created Nov 08, 2011 | popularity not rated yet | comments 0 | with audio podcast

Fat cells in abdomen fuel spread of ovarian cancer

A large pad of fat cells that extends from the stomach and covers the intestines provides nutrients that promote the spread and growth of ovarian cancer, reports a research team based at the University of Chicago in the journal ...

Cancer created Oct 30, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Folate receptors may serve as a front door to ovarian cancer treatment

A new strategy that takes advantage of ovarian cancer's reliance on folate appears to give relapse patients extra months of life with few side effects, researchers say.

Cancer created Oct 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Pill and pregnancy have biggest effects on ovarian cancer risk

(Medical Xpress) -- Taking the Pill for 10 years can reduce the risk of ovarian cancer by almost half (45 per cent), new research part-funded by Cancer Research UK shows today.

Obstetrics & gynaecology created Oct 26, 2011 | popularity not rated yet | comments 0 | with audio podcast

Ovarian cancer patients survive longer with BRCA2 mutated in tumors

Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...

Cancer created Oct 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

BRCA2 genetic mutation associated with improved survival, chemotherapy response in ovarian cancer

Among women with a certain type of high-grade ovarian cancer, having BRCA2 genetic mutations, but not BRCA1, was associated with improved overall survival and improved response to chemotherapy, compared to women with BRCA ...

Cancer created Oct 11, 2011 | popularity not rated yet | comments 0 | with audio podcast

Discovery of gene fusion in ovarian cancer could lead to earlier diagnoses

About 15 percent of cases of an aggressive, difficult-to-detect form of ovarian cancer contain a unique fusion between two neighboring, normally separate genes, say researchers at the Stanford University School of Medicine. ...

Genetics created Sep 20, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New technology used in first fluorescence-guided ovarian cancer surgery

The first fluorescence-guided surgery on an ovarian cancer patient was performed using a cancer cell "homing device" and imaging agent created by a Purdue University researcher.

Cancer created Sep 18, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers find possible key to preventing chemotherapy resistance in ovarian cancer

For patients with ovarian cancer and their physicians, resistance to chemotherapy is a serious concern. However, researchers at Moffitt Cancer Center have identified a molecular pathway that may play a key role in the evolution ...

Cancer created Sep 15, 2011 | popularity not rated yet | comments 0 | with audio podcast

Key function of mutation in hereditary breast and ovarian cancer gene discovered

It is widely known that mutations in the breast cancer susceptibility 1 (BRCA1) gene significantly increase the chance of developing breast and ovarian cancers, but the mechanisms at play are not fully understood. Now, researchers ...

Genetics created Sep 01, 2011 | popularity not rated yet | comments 0 | with audio podcast

Olaparib shows promise in treating ovarian cancer, even without BRCA mutations

The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...

Cancer created Aug 21, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers discover antibody that may help detect ovarian cancer in earliest stages

Using a new approach to developing biomarkers for the very early detection of ovarian cancer, researchers at Rush University Medical Center have identified a molecule in the bloodstream of infertile women that could one day ...

Cancer created Aug 16, 2011 | popularity not rated yet | comments 0 | with audio podcast

Study finds more effective approach against ovarian cancer

In a recent issue of Cancer Research, Daniel J. Powell, Jr., PhD, a research assistant professor of Pathology and Laboratory Medicine and Obstetrics and Gynecology at the Perelman School of Medicine at the University of ...

Cancer created Aug 08, 2011 | popularity not rated yet | comments 0 | with audio podcast

Peptides for fighting ovarian cancer developed

A team of German and Italian EU-funded scientists has designed peptides that can target the protein-protein interface of an enzyme that plays a key part in the DNA synthesis crucial for cancer growth.

Cancer created Aug 08, 2011 | popularity not rated yet | comments 0 | with audio podcast


Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses.

Most (more than 90%) ovarian cancers are classified as "epithelial" and are believed to arise from the surface (epithelium) of the ovary. However, some evidence suggests that the fallopian tube could also be the source of some ovarian cancers. Since the ovaries and tubes are closely related to each other, it is thought that these fallopian cancer cells can mimic ovarian cancer. Other types may arise from the egg cells (germ cell tumor) or supporting cells. These cancers are grouped into the category of gynecologic cancer.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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