Sickle cell disease is characterized by recurrent episodes of "sickle crisis," also known as vaso-occlusive crisis, in which a patient's red blood cells change shape, clump together and block the flow of blood in small vessels ...
Feb 1, 2017
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University of Wisconsin-Madison engineers have developed methods to observe gene editing in action, and they're putting those capabilities to work to improve genetic engineering techniques.
Jan 24, 2017
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A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia. Their gene editing technique provided corrections to the mutations and alleviated the disease in mice, ...
Oct 26, 2016
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A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of ...
Oct 12, 2016
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Some genetic diseases persist for generation after generation because the genes that cause them can benefit human health.
Oct 5, 2016
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Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from ...
Aug 9, 2016
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Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions ...
Jun 6, 2016
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Now that she is a first-time mother of a six-month-old boy, Ashaunta Anderson, MD, MPH, is especially happy to be one of five authors of the just published book, "50 Studies Every Pediatrician Should Know" (Oxford University ...
May 16, 2016
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Two-day-old Ellie Bailey squirms in a hospital bassinet and cries as her tiny left heel is squeezed and then pricked with a needle to draw a blood sample. An Indianapolis hospital technician quickly saturates six circles ...
May 13, 2016
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Researchers at Harvard Medical School and Dana-Farber Cancer Institute report that humans have a surprisingly high number of genes in which one of two copies has been randomly silenced. They suggest that the phenomenon is ...
Feb 4, 2016
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