Journal of Cell Biology

p53 cuts off invading cancer cells

The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate ...

Mar 24, 2014
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How developing sperm stick to the right path

The process of producing high-quality, fertile sperm requires many steps. A study in The Journal of Cell Biology shows how the transcription factor p73 promotes this process by regulating the adhesions betwee ...

Mar 24, 2014
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FAK helps tumor cells enter the bloodstream

Cancer cells have something that every prisoner longs for—a master key that allows them to escape. A study in The Journal of Cell Biology describes how a protein that promotes tumor growth also enables cancer ...

Jan 20, 2014
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