Journal of Cell Biology
Endothelium, heal thyself: A fresh look at this resilient, adaptable tissue
(Medical Xpress)—The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely ...
Medical research
May 16, 2013 |
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Gene offers clues to new treatments for a harmful blood clotting disorder
(Medical Xpress)—A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis—the formation ...
Genetics
May 08, 2013 |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Study uncovers details of early stages in muscle formation and regeneration
(Medical Xpress)—Researchers at the National Institutes of Health have identified proteins that allow muscle cells in mice to form from the fusion of the early stage cells that give rise to the muscle cells.
Medical research
Jan 09, 2013 |
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Scientists identify new molecules important for vision and brain function
In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have identified several proteins that help regulate cells' response to light—and the development of night blindness, ...
Medical research
Jun 11, 2012 |
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Molecule key to sustaining brain communication
(Medical Xpress)—Scientists have discovered the powerful role the molecule Myosin VI plays in communication between nerve cells in the brain.
Medical research
Feb 04, 2013 |
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Protein family linked to autism suppresses the development of inhibitory synapses
Synapse development is promoted by a variety of cell adhesion molecules that connect neurons and organize synaptic proteins. Many of these adhesion molecules are linked to neurodevelopmental disorders; mutations ...
Medical research
Jan 28, 2013 |
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Researchers develop new system to study trigger of cell death in nervous system
(Medical Xpress)—Researchers at the University of Arkansas have developed a new model system to study a receptor protein that controls cell death in both humans and fruit flies, a discovery that could lead to a better understanding ...
Medical research
Apr 03, 2013 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Medical research
Jan 02, 2012 |
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Breast cancer cells spread by digging their escape route
Breast cancer cells puncture holes into neighbouring tissues and crawl though the spaces they create to spread around the body, according to research published in the Journal of Cell Biology.
Cancer
Oct 23, 2012 |
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Kinesin 'chauffeur' helps HIV escape destruction
A study in The Journal of Cell Biology identifies a motor protein that ferries HIV to the plasma membrane, helping the virus escape from macrophages.
HIV & AIDS
Oct 22, 2012 |
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Targeting protein could prevent metastasis of cancer cells
(Medical Xpress)—Researchers at King's College London have uncovered a protein required by cancer cells to spread to other parts of the body, highlighting it as a potential target for future treatments ...
Cancer
Nov 14, 2012 |
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Study unravels biological pathway that controls the leakiness of blood vessels
(Medical Xpress)—A research team led by scientists at Mayo Clinic in Florida have decoded the entire pathway that regulates leakiness of blood vessels—a condition that promotes a wide number of disorders, such as heart ...
Medical research
Dec 17, 2012 |
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Poor recycling of BACE1 enzyme could promote Alzheimer's disease
Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.
Medical research
Nov 21, 2011 |
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