Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction. The study, which will be published December 21 in the Journal of Cell Biology, suggests ...
Dec 21, 2017
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Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin. The study, which will be published December ...
Dec 11, 2017
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One of the most hopeful discoveries of modern neuroscience is firm proof that the human brain is not static following birth. Rather, it is continually renewing itself, via a process called postnatal neurogenesis - literally, ...
Nov 2, 2017
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Keeping the human brain in a healthy state requires a delicate balance between the generation of new cellular material and the destruction of old. Specialized structures known as lysosomes, found in nearly every cell in your ...
Aug 7, 2017
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Researchers from Yale University School of Medicine have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study, ...
Aug 7, 2017
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Researchers from The Ohio State University have discovered how blows to the head cause numerous small swellings along the length of neuronal axons. The study, "Polarity of varicosity initiation in central neuron mechanosensation," ...
Jun 12, 2017
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Researchers at Cold Spring Harbor Laboratory (CSHL) have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. A study they publish today ...
Feb 13, 2017
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A team of researchers led by Patrik Verstreken (VIB–KU Leuven) have identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' ...
Feb 10, 2017
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Research published today, 30th January 2017 online in the Journal of Cell Biology, has for the first time identified how a bodily protein allows nerves of the peripheral nervous system (PNS) to repair following injury.
Jan 30, 2017
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Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer ...
Jan 25, 2017
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