Molecular Cell

Medical research

Study reveals factors behind embryonic stem cell state

Embryonic stem cells (ESC) have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body. The embryonic stem cell state is established and maintained by multiple regulatory ...

Neuroscience

Research reveals how the most common ALS mutation dooms cells

St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The research suggests possible new approaches ...

Oncology & Cancer

Balance of two enzymes linked to pancreatic cancer survival

Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...

Medical research

Scientists find new clues about how the body stores fat

Fat, biologically speaking, is not a bad thing. Fatty acids—the molecular building blocks for body fat—are crucial to the formation of cell walls and for storing energy in the form of glycerolipids. Now, Rockefeller scientists ...

Oncology & Cancer

New drug targets for BRCA-driven cancer uncovered

BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...

page 11 from 18