Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell.
Nov 19, 2020
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Led by professor Ludo Van Den Bosch (VIB-KU Leuven), scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal ...
Mar 17, 2017
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BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...
Jan 24, 2019
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Fanconi anemia is a rare genetic disease characterized by hematologic symptoms that include low platelet count and unusually large red blood cells. Mutations in nearly 20 genes have been identified as causative for Fanconi ...
Jul 10, 2017
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Fat, biologically speaking, is not a bad thing. Fatty acids—the molecular building blocks for body fat—are crucial to the formation of cell walls and for storing energy in the form of glycerolipids. Now, Rockefeller scientists ...
Mar 7, 2019
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Pancreatic cancer is a particularly deadly form of disease, and patients have few options for effective treatment. But a new Yale-led study has identified a gene that is critical to pancreatic cancer cell growth, revealing ...
Aug 11, 2017
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Researchers working in a U of A laboratory have uncovered two previously unknown ways that metabolism triggers cancer cell growth, uncovering potential new pathways for diagnosis and treatment.
May 5, 2022
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Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in specific order. In a study ...
Aug 24, 2017
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In cancer research, it's a common goal to find something about cancer cells—some sort of molecule—that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. ...
Jul 2, 2021
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CU Boulder researchers have discovered a protein's crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that protein kills cancer cells without harming healthy ones.
Apr 13, 2023
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