Molecular Cell

Oncology & Cancer

Team finds a potentially better way to treat liver cancer

A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer, one of the few cancers in the United States with an incidence rate ...

Neuroscience

Research reveals how the most common ALS mutation dooms cells

St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The research suggests possible new approaches ...

Medical research

Mouse and human skin cells produce melanin on a 48-hour cycle

Researchers have discovered that mouse skin and skin cells from humans produce pigmentation in response to sunlight on a 48-hour cycle. They observed that exposing skin to ultraviolet light every 2 days yielded darker pigmentation ...

Neuroscience

Finding a cause of neurodevelopmental disorders

Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a ...

Medical research

'Cellular memory' of DNA damage in oocyte quality control

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal ...

Neuroscience

The mechanism behind the pluripotency-differentiation transition

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells decide ...

Medical research

In cells, some oxidants are needed

Within our bodies, high levels of reactive forms of oxygen can damage proteins and contribute to diabetic complications and many other diseases. But some studies are showing that these reactive oxygen species (ROS) molecules ...

Medical research

Researchers find potential treatment for Rett Syndrome

An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth, Yale researchers report ...

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