Nature Immunology

Immune protein could stop diabetes in its tracks

Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed.

Immunology created May 20, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Study finds immunity protein that ramps up inflammation, and agents that can block it

Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival ...

Immunology created Mar 31, 2013 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast

Study finds how to shutdown cancer's powerful master protein

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex ...

Immunology created Mar 03, 2013 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Team identifies molecular switch enabling immune cells to better fight disease

A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against ...

Immunology created Jan 20, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Survival gene may be key to controlling HIV and hepatitis

(Medical Xpress)—A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis.

Immunology created Nov 26, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists find missing link between stem cells, immune system

UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy ...

Immunology created Sep 02, 2012 | popularity 3.9 / 5 (8) | comments 0 | with audio podcast

Manipulating the microbiome could help manage weight

Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, ...

Immunology created Aug 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Immune system uses heart channel to select powerful defenders

(Medical Xpress) -- When the body makes immune T cells, it relies on a molecular channel more commonly seen in nerves and heart muscles to ensure that the powerful T cells have the right mixture of aggressiveness ...

Immunology created Aug 16, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Key signal prepares immune cells to defend skin, brain

(Medical Xpress) -- Scientists at Washington University School of Medicine in St. Louis have identified the molecular signal that triggers the development of immune cells that patrol the skin and brain.

Immunology created Aug 10, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Control gene for 'conveyor belt' cells could help improve oral vaccines, treat intestinal disease

Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.

Immunology created Jun 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists find new mechanism by which cell signaling pathway contributes to rheumatoid arthritis development

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence ...

Immunology created May 20, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists show how memory B cells stay 'in class' to fight different infections

Scientists at The Scripps Research Institute have made an important discovery about the internal programming of B cells, the immune cells that make antibodies against infections. The finding opens the way for the development ...

Immunology created May 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers discover key to immune cell's 'internal guidance' system

University of British Columbia researchers have discovered the molecular pathway that enables receptors inside immune cells to find, and flag, fragments of pathogens trying to invade a host.

Immunology created Feb 05, 2012 | popularity 5 / 5 (6) | comments 1 | with audio podcast

Not all cytokine-producing cells start out the same way, study finds

(Medical Xpress)—Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory ...

Immunology created May 13, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

T cells rely on 'rheostat' to help ensure that the immune response matches the threat

A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Im ...

Immunology created Apr 30, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast