Nature Methods

Scientists develop alternative to gene therapy: The technique points to safer, simpler potential HIV treatment

Scientists at The Scripps Research Institute have discovered a surprisingly simple and safe method to disrupt specific genes within cells. The scientists highlighted the medical potential of the new technique by demonstrating ...

Medical research Jul 01, 2012 | 5 / 5 (9) | 0 |

'Brainbow,' version 2.0: Researchers refine breakthrough system for producing images of brain, nervous system

(Medical Xpress)—The breakthrough technique that allowed scientists to obtain one-of-a-kind, colorful images of the myriad connections in the brain and nervous system is about to get a significant upgrade.

Neuroscience May 16, 2013 | 5 / 5 (3) | 0 |

Researchers image most of vertebrae brain at single cell level (w/ video)

(Medical Xpress)—Misha Ahrens and Philipp Keller, researchers with the Howard Hughes Medical Institute have succeeded in making a near real-time video of most of a zebrafish's brain showing individual neuron ...

Neuroscience Mar 20, 2013 | 5 / 5 (5) | 0 |

Discovery offers unprecedented look at regulation of gene expression

(Medical Xpress)—A groundbreaking technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression ...

Medical research Jan 25, 2013 | 5 / 5 (2) | 0 |

Uncovering a flaw in drug testing for chronic anxiety disorder

Pre-clinical trials—the stage at which medications or therapies are tested on animals like laboratory mice—is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before ...

Medical research Dec 13, 2012 | 5 / 5 (1) | 0 |

Researchers devise a method for reprogramming cells in urine into neural progenitor cells

(Medical Xpress)—Researchers in China have developed a technique for reprogramming cells found in urine into neural progenitor cells that are capable of growing into neurons. In their paper published in ...

Medical research Dec 10, 2012 | not rated yet | 1 |

Scientists aim to analyse a whole mouse brain under the electron microscope

What happens in the brain when we see, hear, think and remember? To be able to answer questions like this, neuroscientists need information about how the millions of neurons in the brain are connected to ...

Neuroscience Oct 23, 2012 | 3.5 / 5 (6) | 1 |

Cutting through the genomic thicket in search of disease variants

(Medical Xpress)—In the early stages of that vast undertaking known as the Human Genome Project, enthusiasm ran high. The enterprise would be costly and laborious but the clinical rewards, unprecedented. Once the complete ...

Genetics Sep 25, 2012 | not rated yet | 0 |

New method may allow personalized clinical trial for cancer therapies

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy – and may offer a way to further refine personalized cancer treatments.

Cancer Aug 13, 2012 | 5 / 5 (1) | 0 |

Taking a hit or two

Cancer only arises if two or more genes are mutated. Learning which combinations of mutations cause cancer represents an extremely laborious endeavor. In the current issue of the journal Nature Methods Robert Eferl and co ...

Cancer Aug 06, 2012 | not rated yet | 0 |

An 'off' switch for pain: Chemists build light-controlled neural inhibitor

Pain? Just turn it off! It may sound like science fiction, but researchers based in Munich, Berkeley and Bordeaux have now succeeded in inhibiting pain-sensitive neurons on demand, in the laboratory. The crucial element in ...

Medical research Feb 22, 2012 | 5 / 5 (6) | 0 |

Research team takes new approach to studying differences between human and monkey brains

(Medical Xpress) -- In order to provide more insight into how human and monkey brains are similar and how they’re different, a research team has taken a different approach to studying both to find out ...

Neuroscience Feb 06, 2012 | 4.6 / 5 (5) | 2 |

New automated imaging to greatly speed whole-brain mapping efforts

A new technology developed by neuroscientists at Cold Spring Harbor Laboratory (CSHL) transforms the way highly detailed anatomical images can be made of whole brains. Until now, means of obtaining such images ...

Medical research Jan 15, 2012 | 4.3 / 5 (14) | 3 |

Fluorescent protein helps scientists with heart, stem cell research

(Medical Xpress)—A fluorescent protein from a deep-sea jellyfish has helped scientists isolate heart cells in the laboratory, creating an invaluable aid to work on heart disease treatments and extraordinary ...

Medical research Sep 24, 2012 | not rated yet | 0

Gene mapping reveals architecture that controls expression of genes responsible for our sense of smell

Within the nasal cavity, millions of sensory neurons in a postage-stamp-sized patch of tissue called the olfactory epithelium control our sense of smell. Thanks to the exquisitely controlled expression of ...

Genetics May 18, 2012 | 5 / 5 (1) | 1