PLoS Pathogens

HIV exploits a human cytokine in semen to promote its own transmission

A new report suggests that the concentration of one human cytokine, interleukin 7 (IL-7), in the semen of HIV-1-infected men may be a key determinant of the efficiency of HIV-1 transmission to an uninfected female partner. ...

HIV & AIDS Feb 07, 2013 | 5 / 5 (1) | 0

In a fight to the finish, research aims knockout punch at hepatitis B

In research published in the Jan. 24 edition of PLOS Pathogens, Saint Louis University investigators together with collaborators from the University of Missouri and the University of Pittsburgh report a breakthrough in the ...

Diseases, Conditions, Syndromes Feb 04, 2013 | 5 / 5 (2) | 0 |

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases

A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pa ...

Cancer Jan 31, 2013 | 5 / 5 (3) | 1

How the bacterium that plays role in spread of MRSA colonises the human nose

A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. aureus) ...

Diseases, Conditions, Syndromes Jan 28, 2013 | 5 / 5 (1) | 0

Pathogenic bacteria adhering to the human vascular wall triggers vascular damage during meningococcal sepsis

Researchers at the Paris Cardiovascular Research Center (PARCC) have shown how adhesion of Neisseria (N.) meningitidis to human microvessels in a humanized mouse model leads to the characteristic cutaneous lesions of meningoco ...

Diseases, Conditions, Syndromes Jan 24, 2013 | not rated yet | 0

HIV-like viruses in non-human primates have existed much longer than previously thought

Viruses similar to those that cause AIDS in humans were present in non-human primates in Africa at least 5 million years ago and perhaps up to 12 million years ago, according to study published January 24 in the Open Access ...

HIV & AIDS Jan 24, 2013 | not rated yet | 0 |

Weight loss helps to oust worms

Scientists from The University of Manchester have discovered that weight loss plays an important role in the body's response to fighting off intestinal worms.

Diseases, Conditions, Syndromes Jan 17, 2013 | not rated yet | 0 |

Researchers attack HIV's final defenses before drug-resistant mutations emerge

Scientists who study HIV are facing a troubling consequence of their own success. They created drugs that can now give infected patients almost normal life expectancy. However, those same drugs will eventually ...

HIV & AIDS Jan 16, 2013 | 5 / 5 (1) | 0 |

Scientists engineer the Schmallenberg virus genome to understand how to reduce disease caused by the virus

Researchers from the MRC Centre for Virus Research at the University of Glasgow in Scotland have developed methods to synthesize and change the genome of Schmallenberg virus (SBV). SBV is a recently discovered pathogen of ...

Diseases, Conditions, Syndromes Jan 10, 2013 | 5 / 5 (2) | 0 |

Influenza virus: Being the most beneficial mutation is no guarantee of long-term genetic success, research finds

(Medical Xpress)—Wellcome Trust Sanger Institute scientists have used computer modelling to understand why some mutations in a virus gene rise to dominance and become 'fixed' in the genome of the virus, ...

Diseases, Conditions, Syndromes Jan 03, 2013 | 4 / 5 (1) | 0 |

Statin drug shows promise for fighting malaria effects

Researchers have discovered that adding lovastatin, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of ...

Diseases, Conditions, Syndromes Dec 27, 2012 | not rated yet | 0 |

Staphylococcus aureus: Why it just gets up your nose

Diseases, Conditions, Syndromes Dec 27, 2012 | 5 / 5 (1) | 0 |

Research reveals new drug target urgently needed for tuberculosis therapy

One third of the world is infected with the bacterium that causes tuberculosis (TB), a disease that is increasingly difficult to treat because of wide spread resistance to available drugs. Researchers from the Institute of ...

Diseases, Conditions, Syndromes Dec 20, 2012 | not rated yet | 0

Ebola virus uses a protein decoy to subvert the host immune response

In a study published today in the Open Access journal PLOS Pathogens, researchers at Emory University have discovered a potentially important mechanism by which the Ebola virus alters and evades the immune response of its ...

Immunology Dec 13, 2012 | 5 / 5 (1) | 0 |

Researchers find age not factor in immunity to viruses

Our immune system does not shut down with age, says a new study led by McMaster University researchers.

Immunology Dec 13, 2012 | 5 / 5 (2) | 0 |

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