PLoS Pathogens

PLoS Pathogens is an open-access scientific journal published by the Public Library of Science. It publishes research and reviews on the biology of pathogens and host-pathogen interactions. The 2010 impact factor is 9.079.

Impact factor
9.079 (2010)

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Novel mechanism allows Legionella to hide in body

(Medical Xpress)—The feared Legionella pneumophila is responsible for legionellosis, an infectious disease that can lead to pneumonia. To infect humans, this pathogen has developed a complex method that allows it to camouflage ...

Diseases, Conditions, Syndromes created May 20, 2013 | popularity not rated yet | comments 0

New discovery may lead the way to improved whooping cough vaccine

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine. The findings could help reduce the incidence ...

Diseases, Conditions, Syndromes created May 13, 2013 | popularity not rated yet | comments 0

Scientists confirm Justinianic Plague caused by bacterium Yersinia pestis

(Medical Xpress)—From the several pandemics generally called 'pestilences' three are historically recognized as due to plague, but only for the third pandemic of the 19th-21st centuries AD there were microbiological ...

Diseases, Conditions, Syndromes created May 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Malaria parasite protein identified as potential new target for drug treatment

Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments ...

Medical research created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Innate immune system can kill HIV when a viral gene is deactivated

Human cells have an intrinsic capacity to destroy HIV. However, the virus has evolved to contain a gene that blocks this ability. When this gene is removed from the virus, the innate human immune system destroys HIV by mutating ...

HIV & AIDS created Mar 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

New foot-and-mouth vaccine signals huge advance in global disease control

(Medical Xpress)—A new vaccine against foot-and-mouth disease that is safer to produce and easier to store has been developed by scientists from the University of Oxford and The Pirbright Institute.

Diseases, Conditions, Syndromes created Mar 28, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Drug-resistant MRSA bacteria: Here to stay in both hospital, community

(Medical Xpress)—The drug-resistant bacteria known as MRSA, once confined to hospitals but now widespread in communities, will likely continue to exist in both settings as separate strains, according to ...

Diseases, Conditions, Syndromes created Mar 15, 2013 | popularity 4.8 / 5 (5) | comments 7 | with audio podcast

French patients keep HIV at bay despite stopping drugs (Update)

A small French study of 14 HIV patients who have remained healthy for years after stopping drug treatment offers fresh evidence that early medical intervention may lead to a "functional cure" for AIDS, researchers said Thursday.

HIV & AIDS created Mar 14, 2013 | popularity not rated yet | comments 0

Two-pronged immune cell approach could lead to universal shot against flu

Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific ...

Medical research created Mar 14, 2013 | popularity 4.5 / 5 (2) | comments 1 | with audio podcast

Immune finding aids quest for vaccines to beat tropical infections

Scientists are a step closer to developing vaccines for a range of diseases that affect 200 million people, mainly in tropical south-east Asia, Africa and Central America.

Immunology created Mar 14, 2013 | popularity not rated yet | comments 0

Study provides new clues to how flu virus spreads

People may more likely be exposed to the flu through airborne virus than previously thought, according to new research from the University of Maryland School of Public Health. The study also found that when ...

Diseases, Conditions, Syndromes created Mar 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

NIH study sheds light on role of climate in influenza transmission

Two types of environmental conditions—cold-dry and humid-rainy—are associated with seasonal influenza epidemics, according to an epidemiological study led by researchers at the National Institutes of Health's Fogarty ...

Diseases, Conditions, Syndromes created Mar 07, 2013 | popularity not rated yet | comments 0

'Defective' virus surprisingly plays major role in spread of disease

(Medical Xpress)—Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new ...

Diseases, Conditions, Syndromes created Feb 28, 2013 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Promising new method for next-generation live-attenuated viral vaccines against Chikungunya virus

Researchers have successfully applied a novel method of vaccine creation for Chikungunya virus (CHIKV) using a technique called large scale random codon re-encoding. Using this approach, a group from the UMR_D 190, Emerging ...

Medical research created Feb 21, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Deadly virus discovered in bats also jumps species

(Medical Xpress)—Four new forms of hantavirus, one of the most virulent pathogens transmitted from animals to humans, have been identified by international research contributed to by the University of Sydney.

Diseases, Conditions, Syndromes created Feb 08, 2013 | popularity 4.7 / 5 (6) | comments 0 | with audio podcast