Fructose consumption increases risk factors for heart disease

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that adults who consumed high fructose corn syrup for two weeks as 25 percent of their daily calorie requirement had increased blood levels of cholesterol and triglycerides, which have been shown to be indicators of increased risk for heart disease.

The American Heart Association recommends that people consume only five percent of calories as added . The for Americans 2010 suggest an upper limit of
25 percent or less of daily calories consumed as added sugar. To address this discrepancy in recommended consumption levels, researchers examined what happened when young overweight and normal weight adults consumed fructose, high syrup or glucose at the 25 percent upper limit.

"While there is evidence that people who consume sugar are more likely to have heart disease or diabetes, it is controversial as to whether high sugar diets may actually promote these diseases, and dietary guidelines are conflicting," said the study's senior author, Kimber Stanhope, PhD, of the University of California, Davis. "Our findings demonstrate that several factors associated with an elevated risk for cardiovascular disease were increased in individuals consuming 25 percent of their calories as fructose or corn syrup, but consumption of glucose did not have this effect."

In this study, researchers examined 48 adults between the ages of 18 and 40 years and compared the effects of consuming 25 percent of one's daily calorie requirement as glucose, fructose or high fructose corn syrup on risk factors for cardiovascular disease. They found that within two weeks, study participants consuming fructose or high fructose , but not glucose, exhibited increased concentrations of LDL cholesterol, triglycerides and apolipoprotein-B (a protein which can lead to plaques that cause vascular disease).

"These results suggest that consumption of sugar may promote ," said Stanhope. "Additionally our findings provide evidence that the upper limit of 25 percent of daily calories consumed as added sugar as suggested by The Dietary Guidelines for American 2010 may need to be re-evaluated."

Related Stories

Scientists say consumers confused about sugars

Jun 08, 2009

Three top researchers corrected inaccuracies and misunderstandings concerning high fructose corn syrup's impact on the American diet. They also examined how the United States Department of Agriculture (USDA) considers this ...

The not-so-sweet truth about sugar -- a risk choice?

Nov 22, 2010

More and more people have become aware of the dangers of excessive fructose in diet. A new review on fructose in an upcoming issue of the Journal of the American Society of Nephrology (JASN) indicates jus ...

Recommended for you

Female baby boomers with asthma? You may need help

1 hour ago

Women over the age of 65 face numerous barriers to good health: an increased risk for obesity, greater struggles against poverty and higher rates of asthma with worse health outcomes. An article published in the August issue ...

New guidelines help keep asthma out of 'yellow zone'

1 hour ago

If you have asthma, you may have an asthma action plan with a "stoplight system" to help you recognize and respond to changes and understand when symptoms are getting worse and need more attention. If you're in the green ...

User comments

Adjust slider to filter visible comments by rank

Display comments: newest first

knowledge_treehouse
not rated yet Jul 28, 2011
Oligofructose is sweet-tasting, zero-calorie, and naturally occurring in yacon root. A study publicized by the National Institutes of Health determined that although it is not digested by humans, their probiotic intestinal flora eat it; and this contribute to their hosts' healths: http://www.ncbi.n...18418450
deatopmg
not rated yet Jul 30, 2011
search and watch a lecture on youtube for "Sugar, the bitter truth". Professor Lussuk (spelling), UCSF, covers the chemistry and other evidence in the metabolization of fructose. The toxic side effects are clearly evident.