Aligning the eyes: A simpler surgery for a complex condition

People with strabismus (misalignment and limited movement of one or more eyes) are often teased about their crossed-eye appearance; those with more complex, disfiguring strabismus can become socially isolated and develop neck and back problems from having to turn their head to see properly. While surgery can correct eye position, it may require operation on several muscles, causing lengthy recovery, and sometimes overcompensates for the problem, requiring repeat operations. A single, simplified procedure adopted at Children's Hospital Boston has good results, researchers report, and allows for eye position to be fine-tuned in the recovery room or up to a week later, often avoiding re-operation.

In the February , a team led by David Hunter, MD, Chief of Ophthalmology at Children's Hospital Boston, reports the results of a procedure known as superior rectus transposition with adjustable medial rectus recession in 17 patients with complex who could not move an outward. To compensate, patients had to tilt their head far to the side, causing problems with balance.

The new procedure enables outward eye movement by repositioning a muscle that normally moves the eye up. "In transposition surgery, we take a force that's moving the eye up or down and translate some of it over to the side, by moving the muscle over," Hunter explains. "This simplified procedure for a complex and disfiguring problem is changing the lives of these children and adults."

Previous transposition procedures have had unintended consequences, such as over-correcting and reducing the eye's inward movement, or causing the eye to become vertically misaligned (gazing abnormally upward or downward). Repeat operations are then needed.

Unlike earlier procedures, the new procedure adjusts a single muscle, the superior rectus, to rotate the eye into place. In some cases, the medial rectus is also adjusted, but the inferior rectus, the source of previous complications, is left alone. The operation also uses an adjustable sliding "noose" knot to pull the eye muscles. The knot can be tightened or loosened afterward to adjust the eye's position -- in the recovery room or up to a week after surgery.

"As strabismus surgeons, we cannot always guarantee optimal alignment after surgery," says Linda Dagi, MD, director of the Adult Strabismus Program at Children's Hospital Boston and a coauthor on the paper. "For this reason, we have found the adjustable suture technique to be the best option for patients."

In their study, Hunter and colleagues reviewed long-term outcomes of 17 children and adults undergoing the surgery (10 with Duane syndrome, a congenital form of strabismus, and 7 with sixth-nerve palsy).

Overall, horizontal eye movement improved about 45 percent, and inward-turning or crossing of the eye improved by about 75 percent. Outward movement also improved, at only minimal cost to inward movement. Eight of the 17 patients regained depth perception. Three patients with especially complex problems required a repeat operation.

Patients' angle of head turn improved from 28 degrees to a barely noticeable 4 degrees. No patient developed a significant problem with vertical eye alignment, a potential risk of the procedure.

For more on the procedure, view a live Webcast about the operation in a 9-year-old girl.

Reshma Mehendale, MD, was first author on the paper. The study was supported by the Children's Hospital Ophthalmology Foundation, Harvard Catalyst, the Harvard Clinical and Translational Science Center and the National Institutes of Health.

"Superior rectus transposition is a significant simplification of a procedure for patients with a difficult problem that seems to be just as effective as the more complex , and with a lower complication rate," says Hunter. "Almost every patient goes home with their eyes where we want them to be."

Related Stories

Infantile esotropia linked to developmental delays

date Apr 17, 2008

Babies with an eye-alignment disorder called infantile esotropia have delays in motor development milestones, but development “catches up” after corrective surgery, reports a study in the April Journal of AAPOS (American ...

Eye divergence in children triples risk of mental illness

date Nov 26, 2008

Children whose eyes are misaligned and point outward are at significantly increased risk of developing mental illness by early adulthood, according to findings of a Mayo Clinic study published this month in Pediatrics, the of ...

Kids with blocked tear ducts at higher risk for 'lazy eye'

date Oct 12, 2011

Amblyopia, sometimes referred to as "lazy eye," is a cause of poor vision in children. It occurs in about 1.6% to 3.6% of the general population. Early treatment is critical, as the first few years are the most important ...

Recommended for you

Running with prosthetic lower-limbs

date Jun 29, 2015

Researchers at Bournemouth University have been looking at the impact of lower-limb prosthetics on competitive running, specifically looking at whether athletes with prosthesis are at an unfair advantage when running against ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.