Risk of sudden cardiac death up for black patients with HTN
Black patients with hypertension face a significantly increased risk of sudden cardiac death compared with nonblack patients, even after adjusting for multiple confounding variables, according to a study published in the April issue of Heart Rhythm.
(HealthDay) -- Black patients with hypertension face a significantly increased risk of sudden cardiac death (SCD) compared with nonblack patients, even after adjusting for multiple confounding variables, according to a study published in the April issue of Heart Rhythm.
Peter M. Okin, M.D., from Cornell University in New York City, and colleagues examined the incidence of SCD in 533 black and 8,660 nonblack hypertensive patients with electrocardiographic left ventricular hypertrophy. Patients were randomly assigned to losartan- or atenolol-based treatment and were followed for a mean of 4.8 years.
The researchers found that SCD occurred in 1.9 percent of patients. Compared with nonblack patients, the five-year SCD incidence was significantly higher in black patients (3.9 versus 1.9 percent; P = 0.007). In univariate analyses, black patients had a significantly increased risk of SCD (hazard ratio, 1.97; P= 0.015). After adjustment for other sociodemographic and medical variables, black race remained similarly associated with an increased risk of SCD (hazard ratio, 1.98; P = 0.02).
"The higher risk of SCD in black patients persists after adjusting for the higher prevalence of risk factors in black patients, in-treatment blood pressure, and the established predictive value of in-treatment electrocardiographic left ventricular hypertrophy and heart rate for SCD in this population," the authors write.
Several authors disclosed financial ties to pharmaceutical companies, including Merck & Co., which partially supported this research.
More information: Abstract
Full Text
Copyright © 2012 HealthDay. All rights reserved.
-
High blood pressure may be especially lethal for blacks
Apr 10, 2012 |
not rated yet |
0
-
Healthy lifestyle associated with low risk of sudden cardiac death in women
Jul 05, 2011 |
not rated yet |
0
-
Risk factors exposed for sudden cardiac death in post-menopausal women with coronary artery disease
Aug 01, 2011 |
not rated yet |
0
-
Anticancer drugs might be of benefit to sickle-cell patients
Dec 06, 2007 |
not rated yet |
0
-
Black patients at higher risk for colon polyps
Sep 23, 2008 |
not rated yet |
0
-
Motion perception revisited: High Phi effect challenges established motion perception assumptions
Apr 23, 2013 |
3 / 5 (2) |
2
-
Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update)
Apr 02, 2013 |
4.5 / 5 (11) |
5
-
The visual system as economist: Neural resource allocation in visual adaptation
Mar 30, 2013 |
5 / 5 (2) |
9
-
Separate lives: Neuronal and organismal lifespans decoupled
Mar 27, 2013 |
4.9 / 5 (8) |
0
-
Sizing things up: The evolutionary neurobiology of scale invariance
Feb 28, 2013 |
4.8 / 5 (10) |
14
-
The Durability of Bone: Long Falls
1 hour ago
-
Is energy convertible to matter?
3 hours ago
-
Rotating electron as a dipole is this right?
5 hours ago
-
Dipole term in multipole expansion
9 hours ago
-
Bubbles in a Pre-Boiling/Boiling pot of water
11 hours ago
-
Assumptions of Griffith's fracture theory
21 hours ago
- More from Physics Forums - Classical Physics
More news stories
Biodegradable stent proves non-inferior to drug-eluting stent
The Orsiro stent, which is a novel stent platform eluting sirolimus from a biodegradable polymer, demonstrated non-inferiority to the Xience Prime everolimus-eluting stent for the primary angiographic endpoint of in-stent ...
Cardiology
6 hours ago |
not rated yet |
0
Post-approval TAVI registry shows high rates of device success at one year
One-year results from SOURCE XT – one of the largest, post-approval transcatheter aortic valve implantation (TAVI) registries to-date – reported today at EuroPCR 2013 show good clinical outcomes in routine clinical practice, ...
Cardiology
6 hours ago |
not rated yet |
0
Antidepressant reduces stress-induced heart condition
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
Cardiology
7 hours ago |
not rated yet |
0
|
Study identifies superior hypertension treatment, efficacy between sexes
(Medical Xpress)—In a recent subgroup analysis of the largest blood pressure treatment trial in history, University of Alabama at Birmingham (UAB) researchers found that women and men react the same to ...
Cardiology
15 hours ago |
5 / 5 (1) |
0
Evaluating a new way to open clogged arteries
Over the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and metallic stents. While generally effective, each of these treatments ...
Cardiology
16 hours ago |
4.8 / 5 (4) |
0
|
If you can remember it, you can remember it wrong
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
B vitamins could delay dementia
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
Reducing caloric intake delays nerve cell loss
Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...
New sleeping pill poised to hit US markets
An experimental sleeping pill from US drug company Merck is effective at helping people fall and stay asleep, according to reviewers at the US Food and Drug Administration, which could soon approve the new drug.
Insight into the dazzling impact of insulin in cells
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
Drugs found to both prevent and treat Alzheimer's disease in mice
Researchers at USC have found that a class of pharmaceuticals can both prevent and treat Alzheimer's Disease in mice.
