Sun exposure and sun-sensitive skin type decreased risk for pancreatic cancer
High levels of ultraviolet radiation at an individual's birth location, sun-sensitive skin type and a history of skin cancer each decreased risk for pancreatic cancer, according to study results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held here June 18-21.
Rachel Neale, Ph.D., principal investigator at Queensland Institute of Medical Research in Queensland, Australia, presented the results of a population-based, case-control study that adds to the already conflicting data about sun exposure, vitamin D gained from sun exposure and cancer risk.
"Several ecological studies, including one conducted in Australia, have suggested that people living in areas with high sun exposure have lower risk for pancreatic cancer," Neale said. "However, some studies of circulating vitamin D indicate that people with high vitamin D are at increased risk, and one study of vitamin D intake supports this increased risk."
The results of this study support the existing ecological data which indicate that sun exposure has a protective effect against pancreatic cancer.
Neale and colleagues recruited 714 people in Queensland, Australia, between 2007 and 2011. They were matched by age and sex to 709 control participants. All participants were interviewed about socio-demographic information and medical history. In addition, they were asked about the location of their birth, skin cancer history and skin type, defined by skin color, tanning ability and propensity to sunburn.
Using NASA's Total Ozone Mapping Spectrometer, the researchers assigned a level of ultraviolet radiation to each birth location and then split them into thirds based on how much radiation was present.
Participants born in areas with the highest levels of ultraviolet radiation had a 24 percent lower risk for pancreatic cancer compared with those born in areas of low ultraviolet radiation.
In addition, although all skin types had some significant association with pancreatic cancer risk, those classified as having the most sun-sensitive skin had a 49 percent decreased risk for pancreatic cancer compared with those classified as having the least sun-sensitive skin. Finally, participants with a history of skin cancer or other sun-related skin lesions had a 40 percent lower risk for pancreatic cancer than those who had not reported skin lesions.
"There is increasing interest in the role of sun exposure, which has been largely attributed to the effect of vitamin D, on cancer incidence and mortality," Neale explained. "It is important that we understand the risks and benefits of sun exposure because it has implications for public health messages about sun exposure, and possibly about policy related to vitamin D supplementation or food fortification."
Moving forward, Neale recommended that researchers conduct large cohort studies that measure sun exposure comprehensively, and serum vitamin D.
"There are several trials of vitamin D that are either under way or planned, and pooling data from these might give some clue about vitamin D and pancreatic cancer," Neale said.
Provided by American Association for Cancer Research
- Exposure to sunlight may decrease risk of advanced breast cancer by half Oct 18, 2007 | not rated yet | 0
- Sun exposure, vitamin D may lower risk of multiple sclerosis Feb 07, 2011 | not rated yet | 0
- Vitamin D levels appear to be associated with risk of skin cancer, although relationship is complex Aug 15, 2011 | not rated yet | 0
- Variant of vitamin D receptor gene linked to melanoma risk Sep 22, 2008 | not rated yet | 0
- Cancer-causing skin damage is done when young May 10, 2012 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
How can there be a term called "intestinal metaplasia" of stomach
14 hours ago Hello everyone, Ok Stomach's normal epithelium is simple columnar, now in intestinal type of adenocarcinoma of stomach it undergoes "intestinal...
Pressure-volume curve: Elastic Recoil Pressure don't make sense
May 18, 2013 From pressure-volume curve of the lung and chest wall (attached photo), I don't understand why would the elastic recoil pressure of the lung is...
If you became brain-dead, would you want them to pull the plug?
May 17, 2013 I'd want the rest of me to stay alive. Sure it's a lousy way to live but it beats being all-the-way dead. Maybe if I make it 20 years they'll...
MRI bill question
May 15, 2013 Dear PFers, The hospital gave us a $12k bill for one MRI (head with contrast). The people I talked to at the hospital tell me that they do not...
Ratio of Hydrogen of Oxygen in Dessicated Animal Protein
May 13, 2013 As an experiment, for the past few months I've been consuming at least one portion of Jell-O or unflavored Knox gelatin per day. I'm 64, in very...
Alcohol and acetaminophen
May 13, 2013 Edit: sorry for the typo in the title , can't edit I looked around on google quite a bit and it's very hard to find precise information on the...
- More from Physics Forums - Medical Sciences
More news stories
The gap between life expectancy in patients with a mental illness and the general population has widened since 1985 and efforts to reduce this gap should focus on improving physical health, suggest researchers in a paper ...
Cancer 2 hours ago | not rated yet | 0
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer 3 hours ago | not rated yet | 0
A novel transcriptome-based classification of colon cancer that improves the current disease stratification based on clinicopathological variables and common DNA markers is presented in a study published in PLOS Medicine this w ...
Cancer 4 hours ago | not rated yet | 0
A study of veterans at high risk for developing lung cancer shows that low-dose computed tomography (LDCT) can be highly effective in helping clinicians spot tiny lung nodules which, in a small number of patients, may indicate ...
Cancer 5 hours ago | not rated yet | 0
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.
Cancer 7 hours ago | not rated yet | 0
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
9 hours ago | 4 / 5 (4) | 0 |
An experimental sleeping pill from US drug company Merck is effective at helping people fall and stay asleep, according to reviewers at the US Food and Drug Administration, which could soon approve the new drug.
3 hours ago | 5 / 5 (1) | 0
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
7 hours ago | 4.8 / 5 (6) | 0 |
Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...
4 hours ago | 5 / 5 (3) | 0 |
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
5 hours ago | not rated yet | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
9 hours ago | 4.8 / 5 (4) | 0 |