No therapy for 20 percent with stage IV solid tumors

June 23, 2012
No therapy for 20 percent with stage IV solid tumors
About 20 percent of patients diagnosed with stage IV metastatic solid tumors do not receive anticancer treatment, according to a study published online June 15 in Cancer.

(HealthDay) -- About 20 percent of patients diagnosed with stage IV metastatic solid tumors do not receive anticancer treatment, according to a study published online June 15 in Cancer.

Alexander C. Small, of the Mount Sinai School of Medicine in New York City, and associates queried the National Cancer Data Base to identify patients diagnosed with metastatic solid tumors who received neither radiotherapy nor between 2000 and 2008.

The researchers identified 773,233 patients, of whom 20.6 percent received no anticancer treatment. Fifty-five percent of the untreated population was made up of patients with non-small-cell lung cancer. The highest rates of no treatment were seen for patients with cancers of the kidney (25.5 percent) and lung (24 percent), and the lowest rate of no treatment was seen for patients with prostate cancer (11.1 percent). Factors significantly associated with no treatment across all included older age (prevalence ratio [PR] range, 1.37 to 1.49), black race (PR range, 1.05 to 1.32), lack of medical insurance (PR range, 1.47 to 2.46), and lower income for all cancers except uterine (PR range, 0.91 to 0.98 for every $10,000 increase in income).

"A large percentage of patients presenting with advanced solid tumors at the time of their initial receive no anticancer therapy," the authors write. "Further studies are necessary to better define the reasons for this lack of treatment, particularly because these relate to access to care, , and treatment disparities."

One author disclosed to the pharmaceutical industry.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Recommended for you

New treatment options for a fatal leukemia

July 27, 2015

In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the Universities of Zurich and ...

Modified DNA building blocks are cancer's Achilles heel

July 22, 2015

In studying how cells recycle the building blocks of DNA, Ludwig Cancer Research scientists have discovered a potential therapeutic strategy for cancer. They found that normal cells have highly selective mechanisms to ensure ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.