First study of heart 'maps' for kids could help correct rapid rhythms
The first study of a procedure to make three-dimensional "maps" of electrical signals in children's hearts could help cardiologists correct rapid heart rhythms in young patients, according to new research presented at the American Heart Association's Basic Cardiovascular Sciences 2012 Scientific Sessions.
Children with the condition atrioventricular nodal reentrant tachycardia, or AVNRT, suffer from disruptions in the heart's electrical system that cause sudden rapid heart rates. Patients have been successfully treated with cardiac ablation , in which the abnormal tissue that causes the condition is destroyed by freezing (cryoablation).
It can be a difficult procedure because every patient may have a different area of abnormal tissue causing the arrhythmia, so low-voltage mapping is used to create a profile of high- and low-voltage areas of tissue to guide ablation. However, no research has been done on children until now.
"This is the first study to look at this technique in pediatric patients," said Lindsey Malloy, D.O., lead researcher and a cardiology fellow and researcher at University of Iowa Children's Hospital in Iowa City. "It has the potential to improve ablation success rates."
Malloy and her colleagues created three-dimensional voltage maps of the right atrium (upper chamber of the heart), using electrical recordings from inside the heart. They also identified a bridge of low voltage signals surrounded by even lower voltage tissue, a "saddle", or voltage bridge indicating where there was reduced electrical activity.
Twenty-nine patients between the ages of 7 and 20 were included in the study.
Physicians performed guided cryoablation of the abnormal electrical pathway using the bridge identified by voltage mapping. In 25 of 29 patients, there was an adequate voltage bridge to allow guided ablation, while the successful ablation site was within the first three lesions in 15 out of 25 patients.
"This use of voltage-guided mapping of this voltage bridge in AVNRT appears to be both safe and very effective in children while providing for more precise electrically guided ablation," Malloy said.
Provided by American Heart Association
- Mount Sinai first to use visually guided catheter ablation system to treat AFib patient Feb 21, 2012 | not rated yet | 0
- Mount Sinai first in nation to ablate atrial fibrillation using new visually-guided balloon catheter Sep 18, 2009 | not rated yet | 0
- UCLA uses new hybrid, precision heart procedures to help stop deadly arrhythmias Nov 08, 2010 | not rated yet | 0
- The Medical Minute: Putting the freeze on abnormal heart beats Feb 25, 2009 | not rated yet | 0
- Novel imaging approach may assist in predicting success of treatment for atrial fibrillation Oct 07, 2008 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
The Durability of Bone: Long Falls
2 hours ago I am doing a paper on the physics in Valve's Portal and got interested in the "Long Fall Boots" that prevent any damage no matter how far you fall. I...
Is energy convertible to matter?
4 hours ago Can we convert energy to matter?
Rotating electron as a dipole is this right?
6 hours ago An electron as shown by the Stern Gerlach experiment behaves like a dipole (albeit only in one of two states). I have been trying to figure out how...
Dipole term in multipole expansion
10 hours ago Hi. I'm having some difficult in understanding something about the dipole term in a multipole expansion. Griffiths writes the expansion as a sum of...
Bubbles in a Pre-Boiling/Boiling pot of water
11 hours ago How is it that bubbles form on the bottom of a surface of a pot of boiling water? I think that there is probably an elementary answer to this...
Assumptions of Griffith's fracture theory
22 hours ago Any experts on Griffith's fracture theory? I am studying the subject and I am having hard time finding out if the theory is valid for all possible...
- More from Physics Forums - Classical Physics
More news stories
The Orsiro stent, which is a novel stent platform eluting sirolimus from a biodegradable polymer, demonstrated non-inferiority to the Xience Prime everolimus-eluting stent for the primary angiographic endpoint of in-stent ...
Cardiology 7 hours ago | not rated yet | 0
One-year results from SOURCE XT – one of the largest, post-approval transcatheter aortic valve implantation (TAVI) registries to-date – reported today at EuroPCR 2013 show good clinical outcomes in routine clinical practice, ...
Cardiology 7 hours ago | not rated yet | 0
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
Cardiology 8 hours ago | 5 / 5 (1) | 0 |
(Medical Xpress)—In a recent subgroup analysis of the largest blood pressure treatment trial in history, University of Alabama at Birmingham (UAB) researchers found that women and men react the same to ...
Cardiology 16 hours ago | 5 / 5 (1) | 0
(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...
13 hours ago | 4.2 / 5 (5) | 0 |
(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...
11 hours ago | 4.9 / 5 (9) | 0 |
An experimental sleeping pill from US drug company Merck is effective at helping people fall and stay asleep, according to reviewers at the US Food and Drug Administration, which could soon approve the new drug.
6 hours ago | 3 / 5 (2) | 0
Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...
7 hours ago | 5 / 5 (3) | 0 |
Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.
13 hours ago | 4.5 / 5 (6) | 0 |
Researchers at USC have found that a class of pharmaceuticals can both prevent and treat Alzheimer's Disease in mice.
10 hours ago | 5 / 5 (4) | 0 |