Cataract risk up for statin users with type 2 diabetes

Cataract risk up for statin users with type 2 diabetes
Statin use, which is substantially higher in patients with type 2 diabetes, correlates with an increased risk of age-related cataracts, according to a study published in the August issue of Optometry and Vision Science.

(HealthDay) -- Statin use, which is substantially higher in patients with type 2 diabetes, correlates with an increased risk of age-related (AR) cataracts, according to a study published in the August issue of Optometry and Vision Science.

Noting that diabetes is a risk factor for AR , Carolyn M. Machan, O.D., from the University of Waterloo in Canada, and colleagues examined the association between AR cataract, , and reported statin use in a large cohort. The prevalence of statin use was assessed for the 452 patients with type 2 diabetes and the 5,884 patients without diabetes.

The researchers found that, for patients older than 38 years, the prevalence of statin use was 56 percent for those with type 2 diabetes and 16 percent for those without diabetes. There was a significant correlation between type 2 diabetes and nuclear sclerosis (odds ratio [OR], 1.62) and (OR, 1.37). There was a significant correlation between statin use and nuclear sclerosis and posterior subcapsular cataract (OR, 1.48 for both). In statin users the 50 percent probability of cataract occurred at age 51.7 for those with type 2 diabetes and at age 54.9 for those without diabetes. The ages were significantly older (55.1 and 57.3 years, respectively) for non-statin users.

"Regardless of the outcome of further study, the benefits of statin use in people with type 2 diabetes are anticipated to continue to outweigh any associated increased risk of AR cataract," the authors write. "Information provided here can serve public health efforts to educate people on the risks of treatments associated with type 2 diabetes."

More information: Abstract
Full Text

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Economic burden of prediabetes up 74 percent over five years

Nov 20, 2014

The economic burden of diabetes in America continues to climb, exceeding more than $322 billion in excess medical costs and lost productivity in 2012, or more than $1,000 for every American, according to a study being published ...

Gynoid fat resists metabolic risks of obesity

Nov 19, 2014

(HealthDay)—The differences in the developmental profiles of upper-body and lower-body fat depots may explain their opposing associations with obesity-related metabolic disease, according to research published ...

Treating diabetes one meal at a time

Nov 19, 2014

Recent estimates project that as many as one in three American adults will have diabetes in 2050. The American Diabetes Association observes November as American Diabetes Month, and this year's theme is America ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.