Epicardial fat tissue thickness predicts coronary artery disease

Epicardial fat tissue thickness predicts coronary artery disease
Asymptomatic patients with coronary artery disease (CAD) have significantly more epicardial adipose tissue (EAT) than those without CAD, with an average EAT thickness of 2.4 mm or higher predictive of significant CAD, according to a study published online in the August issue of The American Journal of Cardiology.

(HealthDay) -- Asymptomatic patients with coronary artery disease (CAD) have significantly more epicardial adipose tissue (EAT) than those without CAD, with an average EAT thickness of 2.4 mm or higher predictive of significant CAD, according to a study published online in the August issue of The American Journal of Cardiology.

In an effort to evaluate the relationship between EAT thickness and CAD, Gil N. Bachar, M.D., of the Rabin Medical Center in Petah Tiqwa, Israel, and colleagues conducted a study involving 190 with one or more who were referred for computed tomographic angiography.

The researchers found that the mean EAT thickness values were significantly higher in patients with atherosclerosis compared to those without (3.54 ± 1.59 mm versus 1.85 ± 1.28 mm). On receiver operating characteristic analysis, a cut-off EAT value of ≥2.4 mm was established as an indicator of significant coronary artery stenosis (>50 percent diameter). EAT values were significantly higher for patients with metabolic syndrome compared to those without and for patients with a calcium Agatston score >400 compared with <400.

"Together, these results suggest that an increased EAT thickness may serve as a marker for severe atherosclerosis and might also be a risk factor for significant CAD in the general population," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

QRS width on ECG linked to sudden cardiac arrest in CAD

Apr 20, 2012

(HealthDay) -- For patients with coronary artery disease (CAD), QRS width on electrocardiogram and echocardiographic evidence of heart failure are associated with out-of-hospital sudden cardiac arrest (SCA), ...

Recommended for you

New drowning rescue steps could save lives

3 hours ago

A New Zealand researcher from the University of Auckland, Jonathon Webber, is part of an international study team that has come up with a new way to help prevent drowning.

User comments