A new model for predicting recovery after spinal cord injury

August 8, 2012
©2012 Mary Ann Liebert, Inc., publishers

For more than 1 million people in the U.S. living with spinal cord injury, the frightening days and weeks following the injury are filled with uncertainty about their potential for recovery and future independence. A new model based on motor scores at admission and early imaging studies may allow clinicians to predict functional outcomes and guide decision-making for therapy and care-giving needs, as described in an article published in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

The novel prediction model, which combines acute functional measures and evidence of injury on (MRI) including swelling and bleeding around the spinal cord, and which was drawn from two large clinical datasets, could help guide treatment decisions, classification of patents for clinical trials, and counseling of patients and families.

Jefferson Wilson, MD, Michael Fehlings, MD, PhD, from University of Toronto and Toronto Western Hospital, Canada, and colleagues from the U.S. describe the prediction model and its potential applications in the article "A Clinical for Long-Term Functional Outcome after Traumatic Spinal Cord Injury Based on Acute Clinical and Imaging Factors."

"An important goal of medical research is to identify early surrogate markers that could assist treating physicians in determining appropriate therapeutic strategies," says W. Dalton Dietrich, III, PhD, The Miami Project to Cure Paralysis, University of Miami, FL, and Deputy Editor of the Journal. "This article provides important information that could help predict the potential for recovery after SCI and thereby direct treatment options."

Explore further: Spinal cord treatment offers hope

More information: The article is available free on the Journal of Neurotrauma website at http://www.liebertpub.com/neu.

Related Stories

Spinal cord treatment offers hope

November 18, 2011

Queensland University of Technology (QUT) researchers have developed a promising new treatment for spinal cord injury in animals, which could eventually prevent paralysis in thousands of people worldwide every year.

Recommended for you

New insights on how cocaine changes the brain

November 25, 2015

The burst of energy and hyperactivity that comes with a cocaine high is a rather accurate reflection of what's going on in the brain of its users, finds a study published November 25 in Cell Reports. Through experiments conducted ...

Can physical exercise enhance long-term memory?

November 25, 2015

Exercise can enhance the development of new brain cells in the adult brain, a process called adult neurogenesis. These newborn brain cells play an important role in learning and memory. A new study has determined that mice ...

Umbilical cells help eye's neurons connect

November 24, 2015

Cells isolated from human umbilical cord tissue have been shown to produce molecules that help retinal neurons from the eyes of rats grow, connect and survive, according to Duke University researchers working with Janssen ...

Brain connections predict how well you can pay attention

November 24, 2015

During a 1959 television appearance, Jack Kerouac was asked how long it took him to write his novel On The Road. His response – three weeks – amazed the interviewer and ignited an enduring myth that the book was composed ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.