Fructose and sugar substitutes alter gut microbiota
High consumption of fructose, artificial sweeteners, and sugar alcohols affect host-gastrointestinal microbe interactions and may contribute to the development of metabolic disorders and obesity, according to research published in the September issue of Obesity Reviews.
(HealthDay)—High consumption of fructose, artificial sweeteners, and sugar alcohols affect host-gastrointestinal microbe interactions and may contribute to the development of metabolic disorders and obesity, according to research published in the September issue of Obesity Reviews.
Amanda N. Payne, Ph.D., of the Institute of Food, Nutrition, and Health in Zurich, and colleagues performed a comprehensive review of the literature to study how host-microbe interactions may contribute to metabolic disorders and obesity.
The researchers found that the reduced diversity in the fructose- and substitute sugar-laden Western diet caused a loss of diversity in the gastrointestinal tract microflora, leading to the establishment of a "Western" gut microbiome. The adaptive metabolism generated additional metabolic activity for the host, which may have altered energy regulation and gut transit times, triggering enhancement of dietary energy extraction. These differences may be sensed by the immune system, leading to intestinal inflammation which later manifests as endotoxemia.
"The combination of these processes can undoubtedly contribute to development of many metabolic disorders associated with obesity," the authors write. "In conclusion, we suggest obesity treatment and prevention could be effectively achieved by promoting intestinal homeostasis through reintroduction of a balanced and diverse diet."
More information: Abstract
Full Text (subscription or payment may be required)
Journal reference: Obesity Reviews
Copyright © 2012 HealthDay. All rights reserved.
- Endotoxemia influenced by diet type May 03, 2012 | not rated yet | 0
- Study offers insight to how fructose causes obesity, metabolic syndrome Feb 27, 2012 | not rated yet | 0
- Pure fructose frequently confused with high fructose corn syrup Mar 04, 2009 | not rated yet | 0
- Scientists say consumers confused about sugars Jun 08, 2009 | not rated yet | 0
- Too much fructose could leave dieters sugar shocked Dec 12, 2007 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Does a charged particle rotate when traveling through a static Bf?
1 hour ago I have been looking at mass spectrometers, in particular the interactions between the Bf ind of a charged particle in motion in a static Bf of the...
Find a link between physics and assignment problems
2 hours ago Hi ! I've been working about assignments problems and how to solve them. I will have to do a presentation about it in few weeks. However, I'll...
Light as a source of electricity
2 hours ago Hello Dear Fellows! We all know that light is an electromagnetic wave and also we know that an antenna receives EM waves and...
A question about the energy stored in a capacitor.
3 hours ago If we imagine a simple circuit with a battery and a capacitor with negligible internal resistance, the capacitor is charged up to a point where the...
Electric field-Charge inside a metallic shell
5 hours ago I am having few doubts while studying electric field which i am putting here Suppose there is a spherical metallic shell with point charge q1 at...
Change in momentum when a body is thrown up and falls back down.
12 hours ago Say, a body of mass 'm' is thrown at a certain angle with the vertical with certain initial velocity 'u'. The initial momentum of this object is mu....
- More from Physics Forums - Classical Physics
More news stories
(Medical Xpress)—Research by the University of Leeds has shown that very young children appear to reject story book characters who are overweight, but not those who are disabled.
Overweight and Obesity May 16, 2013 | 3 / 5 (1) | 2
(HealthDay)—Weight gain in men and women is predicted by two different genetic variations—so-called polymorphisms, according to a new study from the Netherlands.
Overweight and Obesity May 15, 2013 | 5 / 5 (1) | 0 |
(HealthDay)—Drinking 500 ml of purified water is not associated with increases in resting energy expenditure (REE), according to a study presented at the annual meeting of the European Congress on Obesity, ...
Overweight and Obesity May 14, 2013 | 2 / 5 (2) | 1
(HealthDay)—Reviews that are funded by industry tend to find the evidence weak for a causal link between sugar-sweetened beverages (SSBs) and the increasing prevalence of obesity, while other reviews consider ...
Overweight and Obesity May 14, 2013 | not rated yet | 0
Researchers at the University of Wisconsin have identified a potential new risk factor for obstructive sleep apnea: asthma. Using data from the National Institutes of Health (Heart, Lung, and Blood Institute)-funded Wisconsin ...
2 hours ago | not rated yet | 0 |
A new study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.
2 hours ago | not rated yet | 0 |
The hunt for an HIV vaccine has gobbled up $8 billion in the past decade, and the failure of the most recent efficacy trial has delivered yet another setback to 26 years of efforts.
7 hours ago | not rated yet | 0
In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual ...
3 hours ago | 5 / 5 (1) | 0 |
Scientists at Johns Hopkins have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, ...
3 hours ago | 5 / 5 (1) | 0 |
Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study from researchers at Columbia University shows purified components of the ...
2 hours ago | not rated yet | 0