Safety, efficacy of at-home laser for periobital wrinkles studied

Safety, efficacy of at-home laser for periobital wrinkles studied
A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.

(HealthDay)—A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.

James Leyden, M.D., from the Skin Study Center in Broomall, Penn., and colleagues conducted a multicenter trial consisting of two clinical studies in which 124 subjects performed at-home treatment of periorbital wrinkles using a handheld nonablative fractional . Both studies comprised an active treatment phase, including daily treatments, and twice-weekly treatments in a maintenance phase. Ninety subjects were followed through completion of the maintenance phase and 36 were followed for five months after its completion. An in-person investigator assessment, independent blinded review, and subject self-assessment were used to evaluate treatment.

The researchers found that patients were able to follow instructions for safely using the laser, with good compliance to the protocol, and treatments were well tolerated. Independent blinded evaluations showed an improvement in the Fitzpatrick Wrinkle Scale score by one or more grades in 90 percent of subjects at the end of the active phase and in 79 percent at the end of the maintenance phase. Transient posttreatment erythema was the most prevalent side effect.

"In sum, the test device and at-home was demonstrated to have a favorable safety profile and to be effective at reducing the appearance of periorbital ," the authors write. "Subject compliance was high, treatments were well tolerated, and side effects were minimal and transient."

Two authors disclosed financial ties to Palomar Medical Technologies, which funded the study and manufactures the device used in the study.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Pulsed dye laser effective on port-wine stains in infants

Feb 28, 2012

(HealthDay) -- Pulsed dye laser (PDL) treatment at two-, three-, and four-week intervals is effective for infants with facial port-wine stains (PWS), with minimal short-term side effects, according to a study ...

US approves cell therapy injection for wrinkles

Jun 22, 2011

US regulators have approved a new type of therapy that uses a person's own skin cells to create an injectable cosmetic plumper to smooth out laugh lines, Fibrocell Science said Wednesday.

Recommended for you

Researcher to cancer: 'Resistance will be futile'

6 hours ago

Turning the tables, Katherine Borden at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC) has evoked Star Trek's Borg in her fight against the disease. "Cancer cells rapidly ...

How does prostate cancer form?

8 hours ago

Prostate cancer affects more than 23,000 men this year in the USA however the individual genes that initiate prostate cancer formation are poorly understood. Finding an enzyme that regulates this process ...

Low risk of malignancy for small complex adnexal masses

15 hours ago

(HealthDay)—For older women with small complex adnexal masses, the overall risk of malignancy is low, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.