Just-approved flu vaccine uses newer production method

Just-approved flu vaccine uses newer production method

(HealthDay)—Flucelvax is the first seasonal flu vaccine to be approved by the U.S. Food and Drug Administration using a manufacturing method called cell culture technology, the agency said.

Other flu vaccines are produced inside eggs. But that process takes longer than the newer method and could be harmful to people with egg allergies, the FDA explained. In cell culture technology, are grown inside mammalian .

This technology has been used for decades to produce other vaccines, the agency said, and since it is quicker, it can be used more efficiently to develop flu vaccines rapidly in the event of a pandemic.

Flucelvax was evaluated in clinical studies in the United States and Europe involving some 7,700 people ages 18 to 49. Common side effects included pain, redness, injection-site soreness, headache, and fatigue—reactions typically seen in people given egg-based flu vaccines, the FDA said.

The U.S. Centers for Disease Control and Prevention recommends the annual for anyone 6 months and older.

Flucelvax is produced by Novartis Vaccines and Diagnostics, based in Marburg, Germany.

More information: More Information

add to favorites email to friend print save as pdf

Related Stories

FDA approves flu vaccine for coming season

Aug 14, 2012

(HealthDay) -- The formulation for the vaccine that will help protect against the flu this coming season was approved by the U.S. Food and Drug Administration on Monday.

Cell-based flu shot beats current vaccine: study

Feb 15, 2011

Flu vaccines made from lab-grown cells work at least as well as those derived from viruses cultivated in chicken eggs, the preferred method for 50 years, according to a study released Wednesday.

New development could increase flu vaccine supply

Jun 02, 2011

(Medical Xpress) -- Scientists from the U.S. Food and Drug Administration and the pharmaceutical company Novartis announced today in the journal Science Translational Medicine that they have developed a new adjuvant, or com ...

Germany orders recall of some Novartis flu shots

Oct 25, 2012

(AP)—German authorities ordered a recall Thursday of some batches of Novartis flu vaccine as a precautionary measure after the company reported the appearance of small particles in the manufacturing process.

Recommended for you

Xtoro approved for swimmer's ear

Dec 18, 2014

(HealthDay)—Xtoro (finafloxacin otic suspension) eardrops have been approved by the U.S. Food and Drug Administration to treat swimmer's ear, clinically known as acute otitis externa.

Drug interaction identified for ondansetron, tramadol

Dec 18, 2014

(HealthDay)—In the early postoperative period, ondansetron is associated with increased requirements for tramadol consumption, according to a review and meta-analysis published online Dec. 10 in Anaesthesia.

New system targets germs in donated blood plasma

Dec 17, 2014

(HealthDay)—A new system designed to eliminate germs in donated blood plasma and reduce the risk of transmitting a plasma-borne infection has been approved by the U.S. Food and Drug Administration.

Judge halts Alzheimer's drug swap until July

Dec 16, 2014

A federal judge has ordered an Irish drug manufacturer to halt its plans to discontinue its widely used Alzheimer's medication, allegedly in an effort to drive patients to a newer patented drug.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.