New stem cell research, transplant strategies show promise to improve outcomes, reduce complications

December 9, 2012

Studies of stem cell biology and transplant approaches presented today at the 54th Annual Meeting of the American Society of Hematology (ASH) illustrate how the use of advanced modeling techniques is optimizing stem cells to treat patients with blood disorders, as well as the potential of enhanced treatment strategies to improve the success rate of hematopoietic stem cell (HSC) transplantation for these patients.

Hematopoietic is effectively used today as a form of "replacement" therapy for patients with hard-to-treat blood conditions, providing healthy HSCs to help patients whose bodies cannot properly fight infection or disease on their own. While transplants often lead to long-term remission for many patients, researchers are now challenging traditional assumptions in an effort to further improve success rates while minimizing the remaining risks associated with transplantation.

"As we learn more about the biology and therapeutic use of hematopoietic stem cells to cure , we are able to refine our traditional approaches to reduce complications and deliver better patient benefits," said Vanderson Rocha, MD, PhD, moderator of the press conference and Professor of Hematology of Oxford University, United Kingdom. "We are finding that can be programmed in ways we previously did not think possible, a discovery that may lead to the development of important new therapeutic strategies."

Explore further: Researchers say therapy improves stem cell engraftment in umbilical cord blood transplant recipients

Related Stories

Recommended for you

The tale of the bats, dark matter and a plastic surgeon

October 25, 2016

What happens when a plastic surgeon meets a bat expert zoologist and a paleobiologist? No, it's not a strange Halloween story about spooky bat dinosaurs but rather, a story about a new discovery about bats which may unlock ...

Study links small RNA molecule to pregnancy complication

October 24, 2016

A family of small RNA molecules affects the development of cells that give rise to the placenta - an organ that transfers oxygen and nutrients from mother to fetus—in ways that could contribute to a serious pregnancy complication, ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.