Increases in mean platelet volume after PCI tied to death

Increases in mean platelet volume after PCI tied to death
For patients who undergo percutaneous coronary intervention, mortality is associated with increases in mean platelet volume over time following the procedure, according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

(HealthDay)—For patients who undergo percutaneous coronary intervention (PCI), mortality is associated with increases in mean platelet volume (MPV) over time following the procedure, according to a study published in the Jan. 15 issue of The American Journal of Cardiology.

To examine the correlation between MPV and long-term mortality, Binita Shah, M.D., from the New York University School of Medicine in New York City, and colleagues evaluated MPV at baseline, 30 days, 60 days, 90 days, one year, two years, and three years after PCI in 1,512 patients. The slope of linear regression was used to estimate the speed of change in the MPV. The Social Security Death Index was used to determine mortality.

During a median follow-up of 8.7 years, the researchers found that mortality was 49.3 percent after PCI. There was no significant difference in mortality based on stratification by MPV quartile (first quartile, 50.1 percent; second quartile, 47.7 percent; third quartile, 51.3 percent; fourth quartile, 48.3 percent). Mortality was significantly greater in patients with an increase in the MPV over time after PCI (52.9 percent) than in those with a decrease (44.2 percent) or no change (49.1 percent) in the MPV.

"In conclusion, no association was found between the baseline MPV and long-term mortality in patients undergoing PCI," the authors write. "However, increased mortality was found when the MPV increased over time after PCI. Monitoring the MPV after might play a role in ."

More information: Abstract
Full Text

add to favorites email to friend print save as pdf

Related Stories

BCIS myocardial jeopardy score predicts post-PCI death

Jan 18, 2013

(HealthDay)—The British Cardiovascular Intervention Society myocardial jeopardy score (BCIS-JS) predicts mortality after percutaneous coronary intervention (PCI), according to research published in the ...

Study examines multivessel mortality rates

Dec 29, 2011

(Medical Xpress) -- A new study led by University at Albany School of Public Health Distinguished Professor Emeritus Edward L. Hannan finds a link between higher mortality rates and incomplete revascularization ...

Increased stroke risk at 30-days post-CABG versus PCI

Aug 21, 2012

(HealthDay) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous ...

Recommended for you

Barriers preventing post-stroke care

51 minutes ago

For stroke victims, rehabilitation is crucial to their recovery. But a Flinders University study conducted in Singapore found that rehabilitation rates following discharge from hospital are poor because of gaps in the continuum ...

Home-based rehabilitation for CVD patients

1 hour ago

Patients who are found to suffer from cardiovascular diseases often have long years of treatment ahead of them and are urged to drastically change their lifestyle. But what is probably the most difficult ...

New remote patient monitoring devices available

4 hours ago

(HealthDay)—Several new remote patient monitoring devices with useful applications are available or under development, according to an article published July 8 in Medical Economics.

Monitoring pulse after stroke may prevent a second stroke

15 hours ago

New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of ...

User comments