Increased stroke risk at 30-days post-CABG versus PCI

August 21, 2012
Increased stroke risk at 30-days post-CABG versus PCI
The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft surgery compared to those who undergo percutaneous coronary intervention, according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

(HealthDay) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous coronary intervention (PCI), according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

Tullio Palmerini, M.D., from Policlinico S. Orsola in Bologna, Italy, and colleagues conducted a meta-analysis of 19 trials that included 10,944 patients who were randomized to CABG or PCI.

The researchers found the 30-day rate of stroke to be significantly increased after CABG compared with PCI (1.20 versus 0.34 percent; odds ratio [OR], 2.94). After a median follow-up of 12.1 months, the results were similar (1.83 versus 0.99 percent; OR, 1.67). The relative increase in the risk of stroke observed with CABG compared with PCI at either 30 days or midterm follow-up was not affected by the extent of coronary artery disease (single vessel versus multivessel versus left main). When the outcomes of 33,980 patients from 27 observational studies were analyzed, the results were also similar.

"Coronary revascularization by CABG compared with PCI is associated with an increased risk of stroke at 30 days and at the midterm follow-up," the authors write.

Two authors disclosed financial ties to pharmaceutical companies.

Explore further: CABG still preferred over PCI in patients with triple vessel disease

More information: Abstract
Full Text

Related Stories

CABG still preferred over PCI in patients with triple vessel disease

August 29, 2011
Results from CREDO-Kyoto PCI/CABG Registry Cohort-2 show that percutaneous coronary intervention (PCI) was associated with significantly higher risk for serious adverse events in patients with triple vessel disease than coronary ...

Study shows drop off in coronary artery bypass surgeries for heart patients

May 3, 2011
New research from the University of Pennsylvania School of Medicine shows a substantial decrease in one type of revascularization procedure, coronary artery bypass graft (CABG) surgery, while rates of utilization of the other ...

Study examines exercise testing in asymptomatic patients after coronary revascularization

May 14, 2012
Asymptomatic patients who undergo treadmill exercise echocardiography (ExE) after coronary revascularization may be identified as being at high risk but those patients do not appear to have more favorable outcomes with repeated ...

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

June 22, 2011
Patients with normal left ventricular function who undergo elective unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with drug-eluting stents (DES) had favorable outcomes according to ...

Study examines multivessel mortality rates

December 29, 2011
(Medical Xpress) -- A new study led by University at Albany School of Public Health Distinguished Professor Emeritus Edward L. Hannan finds a link between higher mortality rates and incomplete revascularization procedures ...

Recommended for you

Laser device placed on the heart identifies insufficient oxygenation better than other measures

September 20, 2017
A new device can assess in real time whether the body's tissues are receiving enough oxygen and, placed on the heart, can predict cardiac arrest in critically ill heart patients, report researchers at Boston Children's Hospital ...

Metabolism switch signals end for healing hearts

September 19, 2017
Researchers have identified the process that shuts down the human heart's ability to heal itself, and are now searching for a drug to reverse it.

Beta blockers not needed after heart attack if other medications taken

September 18, 2017
A new study from the University of North Carolina at Chapel Hill finds beta blockers are not needed after a heart attack if heart-attack survivors are taking ACE inhibitors and statins. The study is the first to challenge ...

Which single behavior best prevents high blood pressure?

September 15, 2017
(HealthDay)—You probably already know that certain healthy lifestyle behaviors can reduce your risk of developing high blood pressure, but is any one behavior more important than the others?

RESPECT trial shows closing a small hole in heart may protect against recurrent stroke

September 13, 2017
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial ...

Study shows so-called 'healthy obesity' is harmful to cardiovascular health

September 11, 2017
Clinicians are being warned not to ignore the increased cardiovascular health risks of those who are classed as either 'healthy obese' or deemed to be 'normal weight' but have metabolic abnormalities such as diabetes.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.