Increased stroke risk at 30-days post-CABG versus PCI

August 21, 2012
Increased stroke risk at 30-days post-CABG versus PCI
The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft surgery compared to those who undergo percutaneous coronary intervention, according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

(HealthDay) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous coronary intervention (PCI), according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

Tullio Palmerini, M.D., from Policlinico S. Orsola in Bologna, Italy, and colleagues conducted a meta-analysis of 19 trials that included 10,944 patients who were randomized to CABG or PCI.

The researchers found the 30-day rate of stroke to be significantly increased after CABG compared with PCI (1.20 versus 0.34 percent; odds ratio [OR], 2.94). After a median follow-up of 12.1 months, the results were similar (1.83 versus 0.99 percent; OR, 1.67). The relative increase in the risk of stroke observed with CABG compared with PCI at either 30 days or midterm follow-up was not affected by the extent of coronary artery disease (single vessel versus multivessel versus left main). When the outcomes of 33,980 patients from 27 observational studies were analyzed, the results were also similar.

"Coronary revascularization by CABG compared with PCI is associated with an increased risk of stroke at 30 days and at the midterm follow-up," the authors write.

Two authors disclosed financial ties to pharmaceutical companies.

Explore further: CABG still preferred over PCI in patients with triple vessel disease

More information: Abstract
Full Text

Related Stories

CABG still preferred over PCI in patients with triple vessel disease

August 29, 2011
Results from CREDO-Kyoto PCI/CABG Registry Cohort-2 show that percutaneous coronary intervention (PCI) was associated with significantly higher risk for serious adverse events in patients with triple vessel disease than coronary ...

Study shows drop off in coronary artery bypass surgeries for heart patients

May 3, 2011
New research from the University of Pennsylvania School of Medicine shows a substantial decrease in one type of revascularization procedure, coronary artery bypass graft (CABG) surgery, while rates of utilization of the other ...

Study examines exercise testing in asymptomatic patients after coronary revascularization

May 14, 2012
Asymptomatic patients who undergo treadmill exercise echocardiography (ExE) after coronary revascularization may be identified as being at high risk but those patients do not appear to have more favorable outcomes with repeated ...

Positive results for unprotected left main coronary artery PCI with drug-eluting stents

June 22, 2011
Patients with normal left ventricular function who undergo elective unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with drug-eluting stents (DES) had favorable outcomes according to ...

Study examines multivessel mortality rates

December 29, 2011
(Medical Xpress) -- A new study led by University at Albany School of Public Health Distinguished Professor Emeritus Edward L. Hannan finds a link between higher mortality rates and incomplete revascularization procedures ...

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.