Misled by macronutrients? Researchers suggest alternative diet design
The search for the perfect diet—one that promotes weight loss and optimal health—has left many people empty handed. A Perspectives article written by University of Cincinnati (UC) researchers and appearing in the Feb. 22, 2013, edition of Science suggests that a broad focus on the negative effects of high-fat or processed carbohydrate-rich diets could be misplaced.
Authors Randy Seeley, PhD, and Karen Ryan, PhD, say that rather than focusing on macronutrients that make up food (fats, proteins and sugars), it might be better to focus at an even deeper level—the micronutrients derived from certain foods that act at the cellular level.
They suggest that food should be viewed and studied as if it is a cocktail of "hormones" because of the way its derivatives act on cells within the body.
For example, the authors cite the amino acid leucine—which isn't made in the body and must be ingested. Leucine has been found to trigger brain pathways that reduces food intake and body weight. Leucine micronutrient of many foods including soybeans, some cuts of beef, brown rice, chicken egg yolks and cow's milk.
"What we eat is not just made up of various amounts of fat, protein and sugar," says Seeley, professor of medicine at UC and director of the Cincinnati Diabetes and Obesity Center.
"As food is broken down, its micronutrient components circulate in the blood and act on cell-surface receptors on multiple organs to change the activities of those cells in the same way that hormones made in our body do. In this way our bodies can 'listen' and respond to what foods we are eating."
Seeley says that just as different levels of various hormones can influence our health, so can the "hormones" that come from our food. By viewing food as hormones, Seeley adds, diets could be designed in a "bottom-up" fashion to reduce disease and promote wellness.
"Designing a diet based on how its various micronutrients turn on or off certain receptors in different tissues is a 'bottom-up' way to design diets. "Just as different levels of various hormones can influence our health, so can the 'hormones' that come in from our food."
Journal reference: Science
Provided by University of Cincinnati Academic Health Center
- Brain mechanisms link foods to rising obesity rates Feb 07, 2012 | not rated yet | 0
- System in brain -- target of class of diabetes drugs -- linked to weight gain May 01, 2011 | not rated yet | 0
- 'Starving' fat suppresses appetite Feb 01, 2010 | not rated yet | 0
- Dietary leucine may fight prediabetes, metabolic syndrome Jun 22, 2011 | not rated yet | 0
- Got a craving for fast food? Skip the coffee, study says Apr 01, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
Talking on a hands-free device while behind the wheel can lead to a sharp increase in errors that could imperil other drivers on the road, according to new research from the University of Alberta.
Health 4 hours ago | not rated yet | 0
(HealthDay)—More than one in four of those eligible for new premium assistance tax credits under the Affordable Care Act (ACA) do not have a checking account and will not be able to receive premiums from ...
Health 6 hours ago | not rated yet | 0
After studying noise in one French Quarter neighborhood of New Orleans to determine whether or not noise levels exceeded municipal ordinances, Annette Hurley, PhD, Assistant Professor of Audiology at LSU Health Sciences Center ...
Health 8 hours ago | not rated yet | 0
Young children who missed more than half of recommended well-child visits had up to twice the risk of hospitalization compared to children who attended most of their visits, according to a study published today in the American Jo ...
Health 8 hours ago | not rated yet | 0
The individualisation of drug treatments to support patients to self-manage their conditions is a concept that sits at the heart of policy, but a recent study in BMJ Open shows that there is no concrete defini ...
Health 10 hours ago | 3 / 5 (1) | 0
Two mutations central to the development of infantile myofibromatosis (IM)—a disorder characterized by multiple tumors involving the skin, bone, and soft tissue—may provide new therapeutic targets, according to researchers ...
5 hours ago | 5 / 5 (1) | 0 |
(Medical Xpress)—A new study by researchers in the US has shown that an ancient virus can be modified to help in the fight against the simian immunodeficiency virus SIV, which is the equivalent in monkeys ...
10 hours ago | 5 / 5 (3) | 0 |
Women at a particular stage in their monthly menstrual cycle may be more vulnerable to some of the psychological side-effects associated with stressful experiences, according to a study from UCL.
7 hours ago | 5 / 5 (1) | 0 |
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
8 hours ago | 5 / 5 (2) | 0 |
Kate O'Reilly's spring allergy survival kit includes the usual stuff - nasal sprays, allergy pills and a box of tissues. This season, she's added a new weapon to her line of defense: an app on her smartphone.
5 hours ago | not rated yet | 0