Bird vaccine for West Nile Virus

July 9, 2013

University of British Columbia researchers have developed a vaccine that may halt the spread of West Nile Virus (WNV) among common and endangered bird species.

WNV, a mosquito borne pathogen, arrived in North America in 1999 and is now endemic across the continent. In 2012 alone, WNV killed 286 people in the United States, and 42 people have died from the virus in Canada since 2002. There is currently no effective vaccine against WNV infection in humans or birds.

Common birds such as crows, ravens and jays, and endangered species such as the Greater Sage-Grouse and the Eastern Loggerhead Shrike, are also susceptible to WNV infection, with in some species and populations as high as 100 per cent.

"West Nile Virus has been identified as a threat contributing to the extinction of some rare bird species and its presence in common birds facilitates the spread of the disease," says Joanne Young , lead author of a study recently published in PLOS ONE and a PhD student in UBC's Michael Smith Laboratories and Department of Zoology. "A bird vaccine would go a long way to helping combat these adverse effects."

Young and Prof. Wilfred Jefferies developed and tested a vaccine made from components of WNV and found it generated an effective immune response in birds. This may protect against the spread of virus not only among birds but also to other species. The team will now study the vaccine's effectiveness in protecting birds against mortality caused by the disease.

Explore further: Continental mosquito with 'vector' potential found breeding in UK after 60 year absence

Related Stories

Recommended for you

Monkeys in Asia harbor virus from humans, other species

November 19, 2015

When it comes to spreading viruses, bats are thought to be among the worst. Now a new study of nearly 900 nonhuman primates in Bangladesh and Cambodia shows that macaques harbor more diverse astroviruses, which can cause ...

One-step test for hepatitis C virus infection developed

November 14, 2015

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the ...

Computer model reveals deadly route of Ebola outbreak

November 10, 2015

Using a novel statistical model, a research team led by Columbia University's Mailman School of Public Health mapped the spread of the 2014-2015 Ebola outbreak in Sierra Leone, providing the most detailed picture to date ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.