Peritoneal dialysis as an intervention for stroke patients

Ischemic stroke is characterized by an interruption of the blood supply to the brain, which can lead to brain damage and even death. Excess amounts of the excitatory neurotransmitter glutamate are released during stroke events and further exacerbate brain cell death. Currently, there are no effective strategies for combatting the effects ischemic stroke.

In this issue of the Journal of Clinical Investigation , José Sánchez-Prieto and colleagues at the Universidad Complutense demonstrate that peritoneal dialysis is an effective treatment for reducing glutamate levels in the blood following a stroke event. In a rat model of ischemic stroke, peritoneal dialysis reduced tissue damage in the brain. Furthermore, the authors found that peritoneal dialysis was able to reduce blood glutamate levels in humans undergoing dialysis for .

Together, these data suggest that peritoneal dialysis immediately following ischemic stroke may help preserve brain tissue and function.

More information: Amelioration of ischemic brain damage by peritoneal dialysis, J Clin Invest. DOI: 10.1172/JCI67284

add to favorites email to friend print save as pdf

Related Stories

Snapshot of dialysis: Who's getting treated at home?

Feb 02, 2012

Home-based dialysis treatments are on the rise in both the developing and developed worlds, but developed countries appear to be turning to them less often, according to a study appearing in an upcoming issue of the Journal of ...

Have a brain injury? You may be at higher risk for stroke

Jun 26, 2013

People who have a traumatic brain injury (TBI) may be more likely to have a future stroke, according to research that appears in the June 26, 2013, online issue of Neurology, the medical journal of the American Academy of Neu ...

Recommended for you

What's more effective: Generic or brand-name statins?

8 hours ago

Statins are the most frequently prescribed drugs in the United States and are effective in reducing cardiovascular events. However, evidence suggests that patients do not always take these medications as prescribed and may ...

User comments