Journal of Clinical Investigation

Journal of Clinical Investigation is a journal published by the American Society for Clinical Investigation.

Publisher
American Society for Clinical Investigation
Country
United States
History
1924
Website
http://www.jci.org/
Impact factor
14.152 (2010)

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Medical research

Regulator of cancer 'stemness' discovered

The protein FOXK2 promotes survival of cancer stem cells in ovarian cancer, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

Alzheimer's disease & dementia

Interferon drives cognitive impairment in Alzheimer's disease model

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities. Although scientists do not yet fully understand ...

Medications

Low-dose lithium may slow kidney aging

Best known therapeutically as a treatment for bipolar disorder, lithium has long intrigued researchers with its potential age-defying properties.

Medical research

Kisspeptin: A new drug to treat liver disease?

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

Cardiology

Lymphatic system aids heart repair

Expression of a pro-lymphangiogenic growth factor after heart injury activates the lymphatic system, spurring leukocytes to help clear away dying cells, according to a Northwestern Medicine study published in the Journal ...

Genetics

The surprising twist behind a rare neurological disorder

A fruit fly study, by an international group of researchers, has pinpointed how a genetic mutation causes one of the important molecular machines in our cells to malfunction. The findings provide a biological mechanism behind ...

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