Journal of Clinical Investigation

Journal of Clinical Investigation is a journal published by the American Society for Clinical Investigation.

Publisher
American Society for Clinical Investigation
Country
United States
History
1924
Website
http://www.jci.org/
Impact factor
14.152 (2010)

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Oncology & Cancer

Targeting MAPK4 emerges as a promising therapy for prostate cancer

The battle against late-stage prostate cancer might have found a potential new strategy to combat this deadly disease. Research led by Baylor College of Medicine reveals in the Journal of Clinical Investigation that the enzyme ...

Oncology & Cancer

Combination treatment for common glioma type shows promise in mice

Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health (NIH), researchers tested a novel combination treatment approach on ...

Medical research

Researchers identify muscle factor that controls fat metabolism

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body's glucose ...

Medical research

Inherited immune condition reversed by random DNA change

Researchers at the Garvan Institute of Medical Research have discovered that three patients with a severe genetic immunodeficiency spontaneously repaired the harmful variants in their DNA and restored normal immune function ...

Oncology & Cancer

Study reveals how certain gut bacteria compromise radiotherapy

A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received ...

Medical research

Myeloid immune cells in the blood tied to severe COVID-19

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease. Researchers at Karolinska Institutet in Sweden have now been able to show that patients with severe COVID-19 ...

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