Journal of Clinical Investigation

Journal of Clinical Investigation is a journal published by the American Society for Clinical Investigation.

Publisher
American Society for Clinical Investigation
Country
United States
History
1924
Impact factor
14.152 (2010)

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Neuroscience

'Gut sense' is hardwired, not hormonal

If you've ever felt nauseous before an important presentation, or foggy after a big meal, then you know the power of the gut-brain connection.

Genetics

Genetic variant prompts cells to store fat, fueling obesity

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined. New research ...

Neuroscience

Obesity: The key role of a brain protein revealed

Regardless of how much you exercise or how balanced your diet is, controlling your weight is more brain-related than you might have thought. In a study published in the Journal of Clinical Investigation, researchers from ...

Medical research

Researchers find protein that suppresses muscle repair in mice

Researchers report that a protein known to be important to protein synthesis also influences muscle regeneration and regrowth in an unexpected manner. The discovery, reported in the Journal of Clinical Investigation, could ...

Neuroscience

Study: Protein key to charcot-marie-tooth, other nerve diseases

A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease. The findings point to a pathway to possible treatments for this disease ...

Inflammatory disorders

New therapeutic strategy to prevent gastrointestinal disease

Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical ...

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