Journal of Clinical Investigation

Journal of Clinical Investigation is a journal published by the American Society for Clinical Investigation.

Publisher
American Society for Clinical Investigation
Country
United States
History
1924
Impact factor
14.152 (2010)

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Neuroscience

'Gut sense' is hardwired, not hormonal

If you've ever felt nauseous before an important presentation, or foggy after a big meal, then you know the power of the gut-brain connection.

Genetics

Genetic variant prompts cells to store fat, fueling obesity

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined. New research ...

Medical research

Possible treatment on the horizon for severe dengue disease

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. ...

Diseases, Conditions, Syndromes

Gut microbiome composition could make diarrhea less likely

Antibiotics are known to upset the balance of bacteria in the intestinal tract. In some cases, antibiotics can cause the bacterium Clostridium difficile (C. difficile) to overgrow wildly, causing diarrhea and, in severe cases, ...

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