Journal of Clinical Investigation

Insights on how SHARPIN promotes cancer progression

Researchers at Sanford Burnham Prebys Medical Discovery (SBP) and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex ...

Dec 11, 2017
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PUMA pathway is a weak link in breast cancer metastasis

Substantial advancements have improved the success of chemotherapy, radiation, and surgical treatments for primary breast cancers. However, breast cancer that has spread, or metastasized, to other parts of the body remains ...

Dec 11, 2017
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